Brief report
Freon inhalational abuse presenting with ventricular fibrillation

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Abstract

Inhalation of volatile halogenated hydrocarbons may produce life-threatening cardiac and neurological toxicity. A 15-year-old boy developed ventricular fibrillation immediately after intentional inhalation of a fluorinated hydrocarbon from an automobile air conditioner recharge unit. After the use of intravenous bretylium, a hemodynamically stable sinus tachycardia was restored. Aspiration pneumonitis and rhabdomyolysis complicated his hospital course before complete neurological recovery. The mechanism and treatment of cardiac arrhythmias after volatile fluorinated hydrocarbon inhalation are reviewed.

References (60)

  • M Bass

    Sudden sniffing deaths

    Hum Toxicol

    (1982)
  • A Azar et al.

    Experimental human exposures to fluorocarbon 12 (Dicholordifluoromethane)

    Am Ind Hyg Assoc J

    (1972)
  • RA Kehoe

    Report on human exposure to dichlorodifluoromethane in air

    (1943)
  • MJ Ellenhorn et al.

    Fluorocarbons

  • A Azar et al.

    Cardiac toxicology of aerosol propellants

    JAMA

    (1971)
  • S Zakhari et al.

    Cardiovascular toxicology of aerosol propellants, refrigerants and related solvents

  • DM Aviado

    Comparative cardiotoxicity of fluorocarbons

  • SM Brooks et al.

    Changes occurring after Freon inhalation

    Am Rev Resp Dis

    (1972)
  • GM Sterling et al.

    Effect of aerosol propellants and surfactants on airway resistance

    Thorax

    (1969)
  • WS Harris et al.

    Aerosol propellants depress myocardial contractility

    Clin Res

    (1971)
  • GJ Taylor et al.

    Depression of myocardial contractility of the intact mammal by aerosol propellant inhalation

    Clin Res

    (1971)
  • WS Harris

    Evidence from animals and man that Freon depresses myocardial contractility

    Circulation

    (1971)
  • RA Bielinski

    Arterial hypotension and myocardial depression caused by inhalation of aerosol propellant

    Circulation

    (1971)
  • FE Speizer et al.

    Palpitation rates associated with fluorocarbon exposure in a hospital setting

    N Engl J Med

    (1975)
  • C Steadman et al.

    Abuse of a fire extinguishing agent and sudden death in adolescents

    Med J Aust

    (1984)
  • MA Clark et al.

    Multiple deaths resulting from shipboard exposure trichlorotrifluoroethane

    J Foren Sci

    (1985)
  • RC Kamm

    Fatal arrhythmia following deodorant inhalation

    Forensic Sci

    (1975)
  • DD Campbell et al.

    Health effects among refrigeration repair workers exposed to fluorocarbons

    Br J Ind Med

    (1986)
  • HR Imbus et al.

    Physical examinations of workers exposed to trichlorotrifluoroethane

    Arch Environ Health

    (1972)
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