Research reportTherapeutic efficacy of antidepressants in agitated anxious depression — a meta-analysis of moclobemide studies
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2020, Ultrasonics SonochemistryCitation Excerpt :The effect of phases and graphite in the aGR-Sb2O3 has investigated in the electroanalytical studies of anti-depressant drug imipramine (IMP). IMP is a tricyclic antidepressant drug mostly prescribed for the treatment of depression, and sometimes bed-wetting and anxiety [11]. Also, IMP has been used as a muscle relaxant and pain reliever for patients who have chronic pain associated with autoimmune diseases such as rheumatoid arthritis [12,13].
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2016, Presse MedicaleNew insights into the neurobiological mechanisms of major depressive disorders
2015, General Hospital PsychiatryCitation Excerpt :Nowadays, many treatments rely on the use of selective neurotransmitter reuptake inhibitors in order to improve the symptoms of patients affected with MDD. For instance, the tricyclic antidepressant (TCA) drug imipramine is often used for the treatment of MDD [45,46]. It acts by inhibiting the reuptake of the noradrenaline by the presynaptic cell.
Effect of reversible ligands on oxime-induced reactivation of sarin- and cyclosarin-inhibited human acetylcholinesterase
2015, Toxicology LettersCitation Excerpt :The reversible AChE-ligands, most of them having effective medical applications in various neurological disorders, were found to inhibit human AChE at different concentrations. This result is in agreement with previous results generated with AChE from different species (Delini-Stula et al., 1995; Iwanaga et al., 1994; Lockhart et al., 2000; Loewenick et al., 2001; Woltjer and Milatovic, 2006; Zeldowicz and Buckler, 1965). Donepezil was the most potent reversible AChE-inhibitor in the series of compounds tested as summarized in Table 1.
Intra-lateral septal infusions of folic acid alone or combined with various antidepressant drugs produce antidepressant-like actions in male Wistar rats forced to swim
2012, Progress in Neuro-Psychopharmacology and Biological PsychiatryCitation Excerpt :However, the open field test can be used as an animal model of anxiety (Treit and Fundytus, 1988). Many researchers use it as a complement to the FST to avoid false positive results that can be obtained in the FST, since some antidepressant drugs may also produce sedative effects (Delini-Stula et al., 1995), as fluoxetine or desipramine did. In the present study, we performed the open field test before the test session in the FST, so a possible criticism of our data is that stress from the open field test might affect the results of the FST.