Cell
ArticleImmunoglobulin synthesis by lymphoid cells transformed in vitro by Abelson murine leukemia virus
References (35)
- et al.
Abelson virus-transformed lymphocytes: null cells that modulate H-2
Cell
(1977) - et al.
Synthesis, surface deposition, and secretion of immunoglobulins by Abelson virus-transformed lymphosarcoma cell lines
Cell
(1975) - et al.
Lymphosarcoma: virus-induced thymic-independent disease in mice
Cancer Res.
(1970) - et al.
Candidate for IgD present on murine B-lymphocytes
Nature
(1974) - et al.
A film detection method for tritium-labeled proteins and nucleic acids in polyacrylamide gels
Eur. J. Biochem.
(1974) - et al.
Some aspects of normal and abnormal cell surface genetics
Ann. Rev. Genet.
(1969) - et al.
Studies of generation of B-cell diversity in mouse, man and chicken
Rapid isolation of antigens from cells with a staphylococcus protein A-antibody adsorbant: parameters of the antibody-antigen complexes with protein A
J. Immunol.
(1975)Cleavage of structural proteins during the assembly of the head of bacteriophage T4
Nature
(1970)- et al.
Cell surface immunoglobulin. X. Identification of an IgD-like molecule on the surface of murine splenocytes
J. Exp. Med.
(1974)
Ontogeny of murine B-lymphocytes: development of Ig synthesis and of reactivities to mitogens and to anti-Ig-antibodies
A possible precursor of immunoglobulin light chains
Nature New Biol.
Immunocytology of cultured IgM forming cells of mouse. I. Requirement of phagocytic cell factor for the growth of IgM forming tumor cells in tissue culture
J. Immunol.
Current enigmas in cancer research
Harvey Lectures
In vitro studies on the generation of lymphocyte diversity
Rapid viral induction of plasmacytomas in pristane-primed BALB/c mice
Science
Early morphological changes associated with infection by a murine non thymic lymphatic tumor virus
J. Nat. Cancer Inst.
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