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Metamorphic acceleration following the exposure to lithium and selenium on American bullfrog tadpoles (Lithobates catesbeianus)
2021, Ecotoxicology and Environmental SafetyCitation Excerpt :This biomarker was reduced in all groups as expected for animals under the metamorphic changes. Notwithstanding, LI and SELI groups showed a remarkable reduction in this biomarker, this prominent lethargy may be linked to a central-toxic effect that has been reported in other animals (Smith, 1981; Staunton et al., 1982; Hafen and Wollnik, 1994) when exposed to lithium. Considering that the presence of selenium in the SELI group did not protect the animals from this lethargic effect, we conclude that the alkali metal was able to promote its lethargic effects even in the presence of the chalcogen.
Chronic lithium decreases Nurr1 expression in the rat brain and impairs spatial discrimination
2004, Pharmacology Biochemistry and BehaviorBehavioral and neurochemical differences in an inbred strain of rats
1990, Physiology and Behavior
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