Effects of partial sleep deprivation on the diurnal variation of mood and motor activity in major depression
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2013, Journal of Affective DisordersCitation Excerpt :There was a bidirectional relationship between sleep and mood that total wake time was associated with negative mood in the next morning and evening negative mood was significantly associated with subsequent total wake time (Talbot et al., 2012). High vigilance, high behavioral activation, high levels of confusion, and low levels of tiredness are typical responses to sleep deprivation (Bouhuys et al., 1989, 1995; Selvi et al., 2007; Szuba et al., 1991). Transmitter metabolites found in urine and cerebrospinal fluid indicate the linkages of low peripheral sympathetic activity and high central noradrenergic activity to sleep deprivation (Baumgartner et al., 1990, 1990; Kuhs and Tolle, 1991).
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2013, Sleep Medicine ClinicsCitation Excerpt :A thorough review of early symptoms of mania and depression by Jackson and colleagues,38 identified sleep disturbance as the most common prodrome of manic relapse and the sixth most common prodrome of depressive relapse in BD. In response to experimental sleep deprivation, a substantial proportion of individuals with BD depression show a rapid alleviation of depressed mood, but a subset of participants experienced an onset of hypomania or mania.39–41 Furthermore, a recent cross-sectional study found that patients with BD who habitually slept fewer than 6 hours a night exhibited both greater manic and depressive symptoms relative to patients with BD that slept between 6.5 and 8.5 hours.34
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