Abstract
Introduction
Distal femur fractures make up < 1% of all fractures and 3–6% of all femur fractures. In the literature, both intramedullary nailing (IMN) and locked plating (LP) have shown favorable results, but there is no consensus on a gold standard. The purpose of this systematic review is to compare outcomes of native distal femur fractures treated via IMN versus LP in an effort to determine if one is superior to the other.
Methods
Systematic review of MEDLINE, EMBASE, and Cochrane Library databases was conducted according to PRISMA guidelines. Only articles published within the last ten years were included. Evidence and study quality were evaluated with the MQOE and Oxford Criteria.
Results
Forty-six articles were included in the review. Fractures treated with IMN were found to have a 93.9% union rate, an average time to union of 19.2 weeks, an average arc of motion of 105.1 degrees, with an average of 14.4 degrees of malalignment. Fractures treated with LP were found to have a 90.2% union rate, an average time to union of 20.5 weeks, an average arc of motion of 104 degrees, with an average of 12.6 degrees of malalignment.
Conclusion
Compiled data comparisons revealed no differences in union rate, malalignment, time to union, average arc of motion, or complication rates requiring a return to the operating room. Until higher level randomized data is available, either IMN or LP are acceptable methods of treatment for native distal femur fractures.
Similar content being viewed by others
Data Availability
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
References
Gwathmey, F. W., Jones-Quaidoo, S. M., Kahler, D., et al. (2010). Distal femoral fractures: current concepts. Journal of American Academy of Orthopaedic Surgeons., 18(10), 597–607.
Collinge, C. A., & Wiss, D. A. (2015). In C. M. Court-Brown, J. D. Heckman, W. M. Ricci, & P. Tornetta (Eds.), Rockwood and Green’s Fractures in Adults (8th ed., pp. 2229–2268). Philadelphia: Wolters Kluwer Health.
Higgins, T. F., Pittman, G., Hines, J., et al. (2007). Biomechanical analysis of distal femur fracture fixation: Fixed-angle screw-plate construct versus condylar blade plate. Journal of Orthopaedic Trauma., 21(1), 43–46.
Seifert, J., Stengel, D., Matthes, G., et al. (2003). Retrograde fixation of distal femoral fractures: results using a new nail system. Journal of Orthopaedic Trauma., 17(7), 488–495.
Wright, J. G., Swiontkowski, M. F., & Heckman, J. D. (2003). Introducing levels of evidence to the journal. Journal of Bone and Joint Surgery. American., 85(1), 1–3.
Gill, S., Mittal, A., Raj, M., et al. (2017). Extra articular supracondylar femur fractures managed with locked distal femoral plate or supracondylar nailing: a comparative outcome study. Journal Clinical of Diagnostic Research., 11(5), Rc19-rc23.
Demirtas, A., Azboy, I., Ozkul, E., et al. (2014). Comparison of retrograde intramedullary nailing and bridge plating in the treatment of extra-articular fractures of the distal femur. Acta Orthop Traumatol Turc., 48(5), 521–526.
Gao, K., Gao, W., Huang, J., Li, H., Li, F., Tao, J. (2013). Retrograde nailing versus locked plating of extra-articular distal femoral fractures: comparison of 36 cases. Med Princ Pract., 22(2), 161–166.
Henderson, C. E., Lujan, T., Bottlang, M., et al. (2010). Stabilization of distal femur fractures with intramedullary nails and locking plates: differences in callus formation. Iowa Orthopaedic Journal., 30, 61–68.
Hierholzer, C., von Ruden, C., Potzel, T., et al. (2011). Outcome analysis of retrograde nailing and less invasive stabilization system in distal femoral fractures: a retrospective analysis. Indian Journal of Orthopaedics., 45(3), 243–250.
Hoskins, W., Sheehy, R., Edwards, E. R., et al. (2016). Nails or plates for fracture of the distal femur? Data from the victoria orthopaedic trauma outcomes registry. Bone Joint Journal., 98-b(6), 846–850.
Pean, C. A., Konda, S. R., Fields, A. C., et al. (2015). Perioperative adverse events in distal femur fractures treated with intramedullary nail versus plate and screw fixation. Journal of Orthopaedics., 12, S195-199.
Thomson, A. B., Driver, R., Kregor, P. J., et al. (2008). Long-term functional outcomes after intra-articular distal femur fractures: ORIF versus retrograde intramedullary nailing. Orthopedics., 31(8), 748–750.
Dar, G. N., Tak, S. R., Kangoo, K. A., et al. (2009). Bridge plate osteosynthesis using dynamic condylar screw (DCS) or retrograde intramedullary supracondylar nail (RIMSN) in the treatment of distal femoral fractures: comparison of two methods in a prospective randomized study. Ulus Travma Acil Cerrahi Derg., 15(2), 148–153.
Gurkan, V., Orhun, H., Doganay, M., et al. (2009). Retrograde intramedullary interlocking nailing in fractures of the distal femur. Acta Orthop Traumatol Turc., 43(3), 199–205.
Neubauer, T., Krawany, M., Leitner, L., et al. (2012). Retrograde femoral nailing in elderly patients: outcome and functional results. Orthopedics., 35(6), e855-861.
Cieslik, P., Piekarczyk, P., & Marczynski, W. (2007). Results of retrograde intramedullary nailing for distal femoral fractures–own experience. Orthopaedics Traumatology Rehabilitation., 9(6), 612–617.
Giddie, J., Sawalha, S., & Parker, M. (2015). Retrograde nailing for distal femur fractures in the elderly. Sicot j., 1, 31.
Kim, J., Kang, S. B., Nam, K., et al. (2012). Retrograde intramedullary nailing for distal femur fracture with osteoporosis. Clinical of Orthopaedics Surgery., 4(4), 307–312.
Wu, C. (2015). Retrograde locked intramedullary nailing for aseptic supracondylar femoral nonunion following failed locked plating. Journal of Orthopaedics Surgery., 23(2), 155–159.
Bottlang, M., Fitzpatrick, D. C., Sheerin, D., et al. (2015). Dynamic fixation of distal femur fractures using far cortical locking screws: a prospective observational study. Journal of Orthopaedic Trauma., 28(4), 181–188.
Ehlinger, M., Dujardin, F., Pidhorz, L., et al. (2014). Locked plating for internal fixation of the adult distal femur: influence of the type of construct and hardware on the clinical and radiological outcomes. Orthopaedics Traumatology Surgery Research., 100(5), 549–554.
Erhardt, J. B., Vincenti, M., Pressmar, J., et al. (2014). Mid term results of distal femoral fractures treated with a polyaxial locking plate: a multi-center study. Open Orthopaedics of Journal., 8, 34–40.
Hanschen, M., Aschenbrenner, I. M., Fehske, K., et al. (2014). Mono- versus polyaxial locking plates in distal femur fractures: a prospective randomized multicentre clinical trial. International Orthopaedics., 38(4), 857–863.
Jain, J. K., Asif, N., Ahmad, S., et al. (2013). Locked compression plating for peri- and intra-articular fractures around the knee. Orthopaedics of Surgery., 5(4), 255–260.
Khursheed, O., Wani, M. M., Rashid, S., et al. (2015). Results of treatment of distal extra: articular femur fractures with locking plates using minimally invasive approach–experience with 25 consecutive geriatric patients. Musculoskelet Surgery., 99(2), 139–147.
Pascarella, R., Bettuzzi, C., Bosco, G., et al. (2014). Results in treatment of distal femur fractures using polyaxial locking plate. Strategies Trauma Limb Reconstruction., 9(1), 13–18.
Pawasuttikul, C., & Chantharasap, T. (2014). Open biological reduction and a locking compression plate for distal femoral fractures: a review of 40 cases. Journal of the Medical Association of Thailand., 97(12), 1325–1331.
Virk, J. S., Garg, S. K., Gupta, P., et al. (2016). Distal femur locking plate: the answer to all distal femoral fractures. Journal of Clinical Diagnostic Research., 10(10), Rc01-rc05.
Adams, J. D., Jr., Tanner, S. L., & Jeray, K. J. (2015). Far cortical locking screws in distal femur fractures. Orthopedics., 38(3), e153-156.
Barei, D. P., & Beingessner, D. M. (2012). Open distal femur fractures treated with lateral locked implants: union, secondary bone grafting, and predictive parameters. Orthopedics., 35(6), e843-846.
Batchelor, E., Heal, C., Haladyn, J. K., et al. (2014). Treatment of distal femur fractures in a regional Australian hospital. World Journal of Orthopaedics., 5(3), 379–385.
Chung, J. Y., Cho, J. H., Kweon, H. J., et al. (2016). The use of interfragmentary positional screw in minimally invasive plate osteosynthesis for simple distal femur fractures in elderly patients: a retrospective, single-centre pilot study. Injury, 47(12), 2795–2799.
Doshi, H. K., Wenxian, P., Burgula, M. V., et al. (2013). Clinical outcomes of distal femoral fractures in the geriatric population using locking plates with a minimally invasive approach. Geriatric Orthopaedics Surgery Rehabilitation., 4(1), 16–20.
Gardner, M. J., Toro-Arbelaez, J. B., Harrison, M., et al. (2008). Open reduction and internal fixation of distal femoral nonunions: long-term functional outcomes following a treatment protocol. Journal of Trauma., 64(2), 434–438.
Hart, G. P., Kneisl, J. S., Springer, B. D., et al. (2017). Open reduction vs distal femoral replacement arthroplasty for comminuted distal femur fractures in the patients 70 years and older. Journal of Arthroplasty., 32(1), 202–206.
Harvin, W. H., Oladeji, L. O., Della Rocca, G. J., Murtha, Y. M., Volgas, D. A., Stannard, J. P. (2017). Working length and proximal screw constructs in plate osteosynthesis of distal femur fractures. Injury., 48(11), 2597–2601.
Henderson, C. E., Kuhl, L. L., Fitzpatrick, D. C., et al. (2011). Locking plates for distal femur fractures: is there a problem with fracture healing? Journal of Orthopaedic Trauma., 25(Suppl 1), S8-14.
Kiran Kumar, G. N., Sharma, G., Farooque, K., Sharma, V., Ratan, R., Yadav, S. (2014). Locking Compression Plate in Distal Femoral Intra-Articular Fractures: Our Experience. Int Sch Res Notices., 2014, 1–5.
Kolb, W., Guhlmann, H., Windisch, C., et al. (2008). Fixation of distal femoral fractures with the less invasive stabilization system: a minimally invasive treatment with locked fixed-angle screws. Journal of Trauma., 65(6), 1425–1434.
Linn, M. S., McAndrew, C. M., Prusaczyk, B., et al. (2015). Dynamic locked plating of distal femur fractures. Journal of Orthopaedic Trauma., 29(10), 447–450.
Liu, F., Tao, R., Cao, Y., et al. (2009). The role of LISS (less invasive stabilisation system) in the treatment of peri-knee fractures. Injury, 40(11), 1187–1194.
Lujan, T. J., Henderson, C. E., Madey, S. M., et al. (2010). Locked plating of distal femur fractures leads to inconsistent and asymmetric callus formation. Journal of Orthopaedic Trauma., 24(3), 156–162.
Pakula, G., Kwiatkowski, K., Kuczmera, P., et al. (2015). Assessment of outcomes of treatment of fractures of distal femur with a locking plate taking into account factors influencing the result. Ortopaedics Traumatology Rehabilitation., 17(5), 501–511.
Poole, W. E. C., Wilson, D. G. G., Guthrie, H. C., et al. (2017). “Modern” distal femoral locking plates allow safe, early weight-bearing with a high rate of union and low rate of failure: five-year experience from a United Kingdom major trauma centre. Bone Joint Journal., 99(7), 951–957.
Ricci, W. M., Streubel, P. N., Morshed, S., et al. (2014). Risk factors for failure of locked plate fixation of distal femur fractures: an analysis of 335 cases. Journal of Orthopaedic Trauma., 28(2), 83–89.
Rodriguez, E. K., Zurakowski, D., Herder, L., et al. (2016). Mechanical construct characteristics predisposing to non-union after locked lateral plating of distal femur fractures. Journal of Orthopaedic Trauma., 30(8), 403–408.
Smith, J. R., Halliday, R., Aquilina, A. L., et al. (2015). Distal femoral fractures: the need to review the standard of care. Injury, 46(6), 1084–1088.
Tank, J. C., Schneider, P. S., Davis, E., et al. (2016). Early mechanical failures of the synthes variable angle locking distal femur plate. Journal of Orthopaedic Trauma., 30(1), e7–e11.
Toro, G., Calabrò, G., Toro, A., et al. (2015). Locking plate fixation of distal femoral fractures is a challenging technique: a retrospective review. Clinical Cases in Mineral and Bone Metabolism., 12(Suppl 1), 55.
Vallier, H. A., & Immler, W. (2012). Comparison of the 95-degree angled blade plate and the locking condylar plate for the treatment of distal femoral fractures. Journal of Orthopaedic Trauma., 26(6), 327–332.
Von Keudell, A., Shoji, K., Nasr, M., et al. (2016). Treatment options for distal femur fractures. Journal of Orthopaedic Trauma., S2, S25-27.
Zlodowski, M., Williamson, S., Cole, P. A., et al. (2004). Biomechanical evaluation of the less invasive stabilization system, angled blade plate, and retrograde intramedullary nail for the internal fixation of distal femur fractures. Journal of Orthopaedic Trauma., 18(8), 494–502.
Wahnert, D., Hoffmeier, K. L., von Oldenburg, G., et al. (2010). Internal fixation of type-C distal femur fractures in osteoporotic bone. Journal of Bone and Joint Surgery American., 92(6), 1442–1452.
Ebraheim, N. A., Martin, A., Sochacki, K. R., et al. (2013). Nonunion of distal femoral fractures: a systematic review. Orthopaedic Surgery., 5(1), 46–50.
Kubiak, E. N., Fulkerson, E., Strauss, E., et al. (2006). The evolution of locked plates. Journal of Bone and Joint Surgery American., 88(S4), S189–S200.
Ehlinger, M., Ducrot, G., Adam, P., et al. (2013). Distal femur fractures: surgical techniques and a review of the literature. Orthopaedics and Trauma Surgery and Research., 99, 353–360.
Funding
The authors received no financial support for the research, authorship, and/or publication of this article.
Author information
Authors and Affiliations
Contributions
JJ- study design, literature search, data analysis, manuscript draft. PFS- literature search, manuscript draft. JKS- study design, literature search, data analysis, manuscript draft. DMK- manuscript draft. REP- study design, execution, data interpretation/analysis, manuscript fixation FL- study design, execution, data interpretation/analysis, manuscript fixation. RY- study design, execution, data interpretation/analysis, manuscript fixation. All authors read and approved the final manuscript.
Corresponding author
Ethics declarations
Conflict of interest
Authors have no relevant conflicts of interest or funding to disclose in the preparation and completion of this manuscript.
Ethical standard statement
This article does not contain any studies with human or animal subjects performed by the any of the authors.
Informed consent
For this type of study informed consent is not required.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Jankowski, J.M., Szukics, P.F., Shah, J.K. et al. Comparing Intramedullary Nailing Versus Locked Plating in the Treatment of Native Distal Femur Fractures: Is One Superior to the Other?. JOIO 55, 646–654 (2021). https://doi.org/10.1007/s43465-020-00331-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s43465-020-00331-z