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Evaluation of fluoride concentration in toothpastes with antimicrobial molecules commercialized in Brazil

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A Correction to this article was published on 04 November 2020

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Abstract

Purpose

This study aimed to analyze the fluoride concentrations in different dentifrices with antimicrobial and natural molecules marketed in Brazil. Thus, 12 dentifrices were selected to be analyzed for the concentration of total fluoride (TF), total soluble fluoride (TSF) and ionizable fluoride (IF).

Methods

Two tubes of each brand were purchased at different locations. The samples were analyzed in duplicates using an ion-specific electrode and the concentrations were determined in μg F/g.

Results

The TF of all calcium carbonate dentifrices showed averages below 1500 ppm F. Regarding TSF, only one toothpaste had an average above 1000 ppm F−, while the IF values ​​were almost 500 ppm F. In the analysis of fluoride in dentifrices which present silica as abrasive, the TF presented averages below 1500 ppm F, while the TSF all presented averages close to 1000 ppm F−, and the IF values ​​varied from close to 500 ppm to more than 1000 ppm F. In dentifrices whose formulation contained calcium carbonate associated with silica or other formulations such as sodium bicarbonate, the TF, TSF, and IF values were all above 1000 ppm F.

Conclusion

The evaluated dentifrices generally showed TF concentrations lower than those declared on the packaging; however, the TSF content remained close to 1000 ppm F. It can be concluded that the analyzed dentifrices with antimicrobial molecules showed values ​​close to those suggested regarding anti-caries effect.

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Acknowledgments

The authors acknowledge Brazil University.

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Authors and Affiliations

  1. Biomedical Engineering Postgraduate Program, Brazil University, São Paulo, Brazil

    Maria da Conceição de Araújo Medeiros & Fernanda Roberta Marciano

  2. Development and Technological Innovation in Medicines Postgraduate Program, Federal University of Ceara, Fortaleza, Brazil

    Lídia Audrey Rocha Valadas & Mara Assef Leitão Lotif

  3. Oral Health Research Cluster, Free University of Brussels (VUB), Brussels, Belgium

    Peter Bottenberg

Authors
  1. Maria da Conceição de Araújo Medeiros
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  2. Lídia Audrey Rocha Valadas
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  3. Mara Assef Leitão Lotif
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  4. Peter Bottenberg
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  5. Fernanda Roberta Marciano
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Corresponding author

Correspondence to Lídia Audrey Rocha Valadas.

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The original online version of this article was revised: Table 1: In line D2 it should read Colgate Tripla ação, in D5 it should read Even Juá and in D8 it should read Sorriso Dentes brancos. The heading of Table 2 should read “Comparisons between fluoride concentrations in different toothpastes according to measurement modality (mean difference ± SD) “. The second line should have no numbers and should read: CaCO3: ns *** ****.

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Medeiros, M.d.d., Valadas, L.A.R., Lotif, M.A.L. et al. Evaluation of fluoride concentration in toothpastes with antimicrobial molecules commercialized in Brazil. Res. Biomed. Eng. 37, 9–14 (2021). https://doi.org/10.1007/s42600-020-00094-4

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  • DOI: https://doi.org/10.1007/s42600-020-00094-4

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