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Chemical composition and antimicrobial activity of Teucrium luteum subsp. flavovirens essential oil from Northwestern Algeria

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Abstract

The essential oil (EO) of aerial of Teucrium luteum subsp. flavovirens (Batt.) Greuter & Burdet from Ksour Mountain (Northwestern Algeria) was obtained by hydrodistillation and analyzed by gas chromatography/flame ionization detector (GC/FID) and GC/mass spectrometry (GC/MS). In total, twenty-eight components were identified, representing 98.39% of the total oil containing t-Cadinol (16.33%), Caryophyllene oxide (13.23%); Eudesma-4(15),7-dien-1.β.-ol (7.64%), and β-Pinene (6.77%). Six samples of essential oil of T luteum subsp. flavovirens (TLF) collected from the same location exhibited similar chemical compositions showing a chemical homogeneity. TLF-EO showed the best antimicrobial activity, with minimum inhibitory concentration (MIC) values between 2 and 6 µL/mL. The lowest MIC values (2.0 µL/mL) were measured for Enterococcus faecalis and Pseudomonas aeruginosa.

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References

  • Aburjai T, Hudaib M, Cavrini V (2006) Composition of the essential oil from Jordanian germander (Teucrium polium L.). J Essent Oil Res 18:97–99. https://doi.org/10.1080/10412905.2006.9699398

    Article  CAS  Google Scholar 

  • Aksoy-Sagirli P, Ozsoy N, Ecevit-Genc G, Melikoglu G (2015) In vitro antioxidant activity, cyclooxygenase-2, thioredoxin reductase inhibition and DNA protection properties of Teucrium sandrasicum L. Ind Crops Prod 74:545–550. https://doi.org/10.1016/j.indcrop.2015.05.025

    Article  CAS  Google Scholar 

  • Alwahsh MAA, Khairuddean M, Chong WK (2015) Chemical constituents and antioxidant activity of Teucrium barbeyanum Aschers. Rec Nat Prod 9:159–163

    Google Scholar 

  • Antunes T, Sevinate-Pinto I, Barroso JG, Cavaleiro C, Salgueiro LR (2004) Micromorphology of trichomes and composition of essential oil of Teucrium capitatum. Flavour Fragr J 19:336–340. https://doi.org/10.1002/ffj.1310

    Article  CAS  Google Scholar 

  • Asgharipour MR, Shabankare HG (2017) Comparison of chemical composition of Teucrium polium L. essential oil affected by phenological stages. Bangladesh J Bot 46:583–588

    Google Scholar 

  • Bakkali F, Averbeck S, Averbeck D, Idaomar M (2008) Biological effects of essential oils – A review. Food Chem Toxicol 46:446–475. https://doi.org/10.1016/j.fct.2007.09.106

    Article  CAS  PubMed  Google Scholar 

  • Battandier JA, Trabut LC (1888) Flore de l’Algérie. Dicotylédones. Alger, Paris

    Google Scholar 

  • Belmekki N, Bendimerad N, Bekhechi C (2013) Chemical analysis and antimicrobial activity of Teucrium polium L. essential oil from Western Algeria. J Med Plants Res 7:897–902. https://doi.org/10.5897/JMPR12.1160

    Article  CAS  Google Scholar 

  • Boulila A, Béjaoui A, Messaoud C, Boussaid M (2008) Variation of volatiles in Tunisian populations of Teucrium polium L. (Lamiaceae). Chem Biodivers 5:1389–1400. https://doi.org/10.1002/cbdv.200890127

    Article  CAS  PubMed  Google Scholar 

  • Chemsa AE, Zellagui A, Öztürk M, Erol E, Ceylan O, Duru ME, Lahouel M (2018) Chemical composition, antioxidant, anticholinesterase, antimicrobial and antibiofilm activities of essential oil and methanolic extract of Anthemis stiparum subsp. sabulicola (Pomel) Oberpr. Microb Pathog 119:233–240. https://doi.org/10.1016/j.micpath.2018.04.033

  • Claeson P, Rådström P, Sköld O, Nilsson Ã, Höglund S (1992) Bactericidal effect of the sesquiterpene t-cadinol on Staphylococcus aureus. Phyther Res 6:94–98. https://doi.org/10.1002/ptr.2650060209

    Article  CAS  Google Scholar 

  • Djabou N, Muselli A, Allali H, Dib MEA, Tabti B, Varesi L, Costa J (2012) Chemical and genetic diversity of two Mediterranean subspecies of Teucrium polium L. Phytochemistry 83:51–62. https://doi.org/10.1016/j.phytochem.2012.05.019

    Article  CAS  PubMed  Google Scholar 

  • Djabou N, Andreani S, Varesi L, Tomi F, Costa J, Muselli A (2013) Analysis of the volatile fraction of Teucrium marum L. Flavour Fragr J 28:14–24. https://doi.org/10.1002/ffj.3120

    Article  CAS  Google Scholar 

  • Dobignard A, Chatelain C (2012) Index synonymique de la flore d’Afrique du Nord: Dicotyledonae, Fabaceae à Nymphaeaceae. Editions des Conservatoire et Jardin botaniques de la Ville de Genève, Genève

    Google Scholar 

  • Gordo B (2021) Analyse de la flore et de la végétation des Monts des Ksour. Université Oran 1

  • Gordo B, Hadjadj-Aoul S (2019) L’endémisme floristique algéro-marocain dans les monts des Ksour (Naâma, Algérie). Flora Mediterr 29:129–142. https://doi.org/10.7320/flmedit29.129

    Article  Google Scholar 

  • Hammoudi R, Hadj Mahammed M, Ould El Hadj MD (2013) Chemical composition and antioxidant and antimicrobial activities of the essential oil from Teucrium polium geyrii (Labiatae). J Med Plants Res 7:1506–1510. https://doi.org/10.5897/JMPR2013.5082

    Article  CAS  Google Scholar 

  • Hasani-Ranjbar S, Nayebi N, Larijani B, Abdollahi M (2010) A systematic review of the efficacy and safety of Teucrium species; from antioxidant to anti-diabetic effects. IJP- Int J Pharmacol 6:315–325. https://doi.org/10.3923/ijp.2010.315.325

    Article  Google Scholar 

  • Imen D, Soumaya H-H, Imed C, Jouda MBJ, Ahmed L, Rym C (2021) Essential oil from flowering tops of Lavandula dentata (L): chemical composition, antimicrobial, antioxidant and insecticidal activities. J Essent Oil Bear Plants 24:632–647. https://doi.org/10.1080/0972060X.2021.1944326

    Article  CAS  Google Scholar 

  • Kovacevic NN, Lakusic BS, Ristic MS (2001) Composition of the essential oils of seven Teucrium species from Serbia and Montenegro. J Essent Oil Res 13:163–165. https://doi.org/10.1080/10412905.2001.9699649

    Article  CAS  Google Scholar 

  • Kremer D, Joze Kosir I, Kosalec I, Zovko Koncic M, Potocnik T, Cerenak A, Bezic S, Dunkic V (2013) Investigation of chemical compounds, antioxidant and antimicrobial properties of Teucrium arduini L. (Lamiaceae). Curr Drug Targets 14:1006–1014. https://doi.org/10.2174/1389450111314090009

  • Kumar D, Punetha A, Verma PPS, Padalia RC (2022) Micronutrient-based approach to increase yield and quality of essential oil in aromatic crops. J Appl Res Med Aromat Plants 26:100361. https://doi.org/10.1016/j.jarmap.2021.100361

    Article  CAS  Google Scholar 

  • Maire R (1916) La vegetation des montagnes du Sud Oranais. Bulletin de la Société d’histoire naturelle de l’Afrique du nord. Imprimerie S. Crescenzo, Alger, pp 210–292

    Google Scholar 

  • Moghtader M (2009) Chemical composition of the essential oil of Teucrium polium L. from Iran. Am J Agric Environ Sci 5:843–846

    CAS  Google Scholar 

  • Navarro T (2020) Systematics and biogeography of the genus Teucrium (Lamiaceae). In: Stanković M (ed) Teucrium species: Biology and applications. Springer International Publishing, Cham, pp 1–38

    Google Scholar 

  • NCCLS (National Committee for Clinical Laboratory Standards), Performance standards for antimicrobial susceptibility testing, ninth informational supplement. Wayne, Pennsylvania, document M100-S9, vol 19, no 1 (1999)

  • Oualidi J, El, Puech S, Navarro T (2002) Geographical variation and successive adaptive radiations of yellow-flowered Teucrium (Labiatae) in the Mediterranean region. Bot Rev 68:209. https://doi.org/10.1663/0006-8101(2002)068[0209:GVASAR]2.0.CO;2

    Article  Google Scholar 

  • Ouknin M, Chibane M, Desjobert JM, Costa J, Majidi L (2019) Chemical profiling study and antioxidant activity of wild Teucrium luteum subsp. flavovirens essential oil from Morocco.J Appl Pharmac Sci 9:98–102. https://doi.org/10.7324/JAPS.2019.91013

  • POWO (2019) Plants of the world online. Facilitated by the Royal Botanic Gardens, Kew. http://www.plantsoftheworldonline.org/. Accessed 11 June 2021

  • Puech S (1982) Contribution à l’étude des Teucrium de la section polium de Tunisie. Bull la Société Bot Fr Lettres Bot 129:41–52. https://doi.org/10.1080/01811797.1982.10824526

    Article  Google Scholar 

  • Pyne SG, Liawruangrath B, Liawruangrath S, Garson M, Khamsan S, Teerawutkulrag A (2011) Antimalarial, anticancer, antimicrobial activities and chemical constituents of essential oil from the aerial parts of Cyperus kyllingia Endl. Rec Nat Prod 5:324–327

    Google Scholar 

  • Radulescu V, Oprea E (2008) Analysis of volatile compounds of officinal Tiliae flos by gas-chromatography coupled with mass spectrometry. Farmacia 56:129–138

    CAS  Google Scholar 

  • Saleh I, Abd-ElGawad A, El Gendy AE-N, Abd El Aty A, Mohamed T, Kassem H, Aldosri F, Elshamy A, Hegazy M-EF (2020) Phytotoxic and antimicrobial activities of Teucrium polium and Thymusdecussatus essential oils extracted using hydrodistillation and microwave-assisted techniques. Plants 9:716. https://doi.org/10.3390/plants9060716

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Saroglou V, Arfan M, Shabir A, Hadjipavlou-Litina D, Skaltsa H (2007) Composition and antioxidant activity of the essential oil of Teucrium royleanum Wall. ex Benth growing in Pakistan. Flavour Fragr J 22:154–157. https://doi.org/10.1002/ffj.1774

    Article  CAS  Google Scholar 

  • Stultz C, Dorman F (2020) Characterization of 9 gas chromatography columns by Kovats and Lee retention indices for dioxin analysis. J Chromatogr A 1614:460701. https://doi.org/10.1016/j.chroma.2019.460701

    Article  CAS  PubMed  Google Scholar 

  • Toiu A, Muntean E, Oniga I, TĂMAŞ M (2009) Pharmacognostic research on Viola declinata Waldst. et Kit.(Violaceae). Farmacia 57:218–222

    CAS  Google Scholar 

  • Znini M, Costa J, Majidi L (2021) Chemical constituents of the essential oil of endemic Teucrium luteum subsp. flavovirens (batt.) Greuter & burdet collected from two localities in Morocco. J Essent Oil Res 33:197–203. https://doi.org/10.1080/10412905.2020.1857853

    Article  CAS  Google Scholar 

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Acknowledgements

We thank all the staff of the Laboratory of Sustainable Management of Natural Resources in Aridand Semi-Arid Areas, who helped us in this study. The authors would like to thank B.Gordo (University of Nâama, Algeria) for the identification of the plant material.

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  1. Mohammed Gherib

    Present address: Department of SNV, Institute of Science and Technology, Salhi Ahmed University Center, Naama, Algeria

Authors and Affiliations

  1. Laboratoire Gestion durable des ressources naturelles dans des zones arides et semi-arides, Département de SNV, Institut des sciences et technologies, Centre Universiaire Salhi Ahmed, Naama, Algeria

    Mohammed Gherib, Belkacem Gordo, Miloud Bouafia, Khalil Chami, Sanaa Fillali & Abdel Ilah Amrouche

  2. Université de Ain Témouchent, route de Sidi bel abbès, N101, 46000, Ain Témouchent, Algeria

    Mohammed Ziane

  3. Laboratory of Transmissible Diseases and Biologically Active Substances (LR99ES27), Faculty of Pharmacy, University of Monastir, Monastir, Tunisia

    Olfa Ben Braik

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  1. Mohammed Gherib
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Gherib, M., Gordo, B., Ziane, M. et al. Chemical composition and antimicrobial activity of Teucrium luteum subsp. flavovirens essential oil from Northwestern Algeria. Vegetos 36, 534–541 (2023). https://doi.org/10.1007/s42535-022-00387-2

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