Skip to main content
SpringerLink
Log in

Synthesis and bioactivity of a novel bismuthoxide Schiff-base complex derived from Salen-like ligand and bismuth(III) nitrate

  • Published:
Chemical Research in Chinese Universities Aims and scope

Abstract

In this paper, a novel bismuthoxide Schiff-base complex [Bi9O8(vanen)3(NO3)2(CH3OH)2(H2O)·3NO3·5.5H2O](abbreviated as Bivanen) was synthesized with Salen-like ligand[H2vanen=N,N’-ethylene bis(3-methoxy-salicylideneimine)] and bismuth(III) nitrate. Its structure was characterized by IR spectra, NMR spectra and X-ray diffraction. In particular, the biology activities of the ligand and the complex against Schizosaccharomyces pombe (S. pombe) were studied using biological microcalorimetry. The metabolic thermogenic curves of S. pombe were measured at 32.00 °C. Then, some quantitative thermokinetic parameters of growth metabolism of S. pombe including the rate constant(k), inhibition ratio(I) and half inhibition concentration(IC50) were calculated. Experimental results showed that the k values of S. pombe decreased while I values of S. pombe increased with the increase of concentrations of the ligand and the complex. The IC50 of the ligand and the complex were found to be 0.067 and 0.037 mmol/L, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Guo Z., Sadler P. J., Angew. Chem. Int. Ed., 1999, 38, 1512

    Article  CAS  Google Scholar 

  2. Thompson K. H., Orvig C., Science, 2003, 300, 936

    Article  CAS  Google Scholar 

  3. Suerbaum S., Michetti P., New Engl. J. Med., 2003, 347, 1175

    Article  Google Scholar 

  4. Sox T. E., Olsen C. A., Antimicrob. Agents Chemother., 1989, 33, 2076

    Article  Google Scholar 

  5. Slikkerveer A., de Wolff F. A., Med. Toxicol. Adverse Drug Exp., 1989, 4, 303

    Article  CAS  Google Scholar 

  6. Graham D. Y., Lew G. M., Evans D. G., Klein P. D., Ann. Intern. Med., 1991, 115, 266

    Article  CAS  Google Scholar 

  7. Chiba N., Can. J. Gastro., 2000, 14, 885

    CAS  Google Scholar 

  8. Houghton J., Fox J. G., Wang T. C., Eur. J. Gastroenterol. Hepatol., 2002, 17, 495

    Article  CAS  Google Scholar 

  9. Marchi S., Costa F., Bellini M., Belcari C., Mumolo M. G., Tornar A., Spisni R., Torelli E., Maltinti G., Eur. J. Gastroenterol. Hepatol., 2001, 13, 547

    Article  CAS  Google Scholar 

  10. Andrews P. C., Deacon G. B., Forsyth C. M., Junk P. C., Kumar I., Maguire M., Angew. Chem. Int. Ed., 2006, 45, 5638

    Article  CAS  Google Scholar 

  11. Thurston J. H., Marlier E. M., Whitmire K. H., Chem. Commun., 2002, 23, 2834

    Article  Google Scholar 

  12. Burford N., Eelman M. D., Cameron T. S., Chem. Commun., 2002, 13, 1402

    Article  Google Scholar 

  13. Andrews P. C., Deacon G. B., Jackson W. R., Maguire M., Scott N., Skelton B. W., White A. H., J. Chem. Soc. Dalton Trans., 2002, 24, 4634

    Article  Google Scholar 

  14. Thurston J. H., Whitmire K. H., Inorg. Chem., 2002, 41, 4194

    Article  CAS  Google Scholar 

  15. Kong W. J., Zhao Y. L., Xing X. Y., Ma X., Sun X. J., Yang M. H., Xiao X. H., Appl. Microbiol. Biotechnol., 2015, 99, 6049

    Article  CAS  Google Scholar 

  16. Wu Y. W., Gao W. Y., Xiao X. H., Liu Y., Thermochim. Acta, 2005, 429, 167

    Article  CAS  Google Scholar 

  17. Cortes J. C., Carnero E., Ishiguro J., Sánchez Y., Durán A., Ribas J. C., J. Cell. Sci., 2005, 118, 157

    Article  CAS  Google Scholar 

  18. Li Q. G., Yang D. J., Li X, Ye L. J., Wei D. L., Xiao S. X., Acta Chim. Sinica, 2008, 66(24), 2686

    CAS  Google Scholar 

  19. Li X., Li Q. G., Zhang H., Hu J. L., Yao F. H., Yang D. J., Xiao S. X., Ye L. J., Huang Y., Guo D. C., Biol. Trace Elem. Res., 2012, 147, 366

    Article  CAS  Google Scholar 

  20. Li X., Jiang J. H., Chen Q., Xiao S. X., Li C. H., Gu H. W., Zhang H., Hu J. L., Yao F. H., Li Q. G., Eur. J. Med. Chem., 2013, 62, 605

    Article  CAS  Google Scholar 

  21. Aguiari A., Bullita E., Casellato U., Guerriero P., Tamburini S., Vigato P. A., Russo U., Inorg. Chim. Acta, 1994, 219, 135

    Article  CAS  Google Scholar 

  22. Ruiz-Martínez A., Casanova D., Alvarez S., Dalton Trans., 2008, 19, 2583

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Hunan Provincial Key Laboratory of Xiangnan Rare-precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou, 423000, P. R. China

    Chuanhua Li, Jianhong Jiang, Xu Li, Shengxiong Xiao, Deliang Wei, Chao Jiang, Jinqi Xie, Mengna Peng & Qiangguo Li

  2. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China

    Huiwen Gu

Authors
  1. Chuanhua Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jianhong Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Xu Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Shengxiong Xiao
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Deliang Wei
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Chao Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Jinqi Xie
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Mengna Peng
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Huiwen Gu
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Qiangguo Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Huiwen Gu or Qiangguo Li.

Additional information

Supported by the National Natural Science Foundation of China(Nos. 21273190, 20973145) and the Science and Technology Plan Projects of Hunan Province, China(Nos. 2014FJ3011, 2013FJ3033, 2014TT2026).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, C., Jiang, J., Li, X. et al. Synthesis and bioactivity of a novel bismuthoxide Schiff-base complex derived from Salen-like ligand and bismuth(III) nitrate. Chem. Res. Chin. Univ. 32, 207–211 (2016). https://doi.org/10.1007/s40242-016-5350-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40242-016-5350-0

Keywords

Search

Navigation