Abstract
Objective
The aim of this study was to evaluate the status of scientific research output of omics in regards to human diseases with more attention shifted toward endocrine and metabolism disorders in Iran, in order to find scientific gaps and also to design future plans for further investigations in this field.
Methods
Extensive search was performed in the electronic databases of Scopus and PubMed, and documents published by Iranian authors up to 27 December 2020 were extracted. Articles related to human diseases were included and categorized based on their types and topics.
Results
A total of 904 publications were found. Followed by checking their titles and abstracts, 327 studies were included. The trend of publication has been increasing during the past years. Regarding this subject, the highest number of publications was in the field of malignant disorders with 82 publications followed by reproductive system diseases and infectious diseases with 33 publications in each subject. Only 12 articles were found in the field of endocrinology and metabolism. The most popular techniques used in those reports were two-dimensional electrophoresis coupled with mass spectrometry (34.4 %) followed by NMR (22.6 %), LC/MS/MS (15 %).
Conclusions
Omics studies in Iran are a relatively new approach and the number of original articles regarding endocrine disorders in humans is limited. Providing appropriate infrastructures including lab facilities with high technology instruments can improve the quality and quantity of basic and clinical researches in this field.
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Data availability
The dataset supporting the conclusions of this article is available and can be accessed by contacting the Corresponding Author.
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All authors participated and approved the paper prior to submission. Hossein Aazami led survey implementation. Shaghayegh Hosseinkhani and Niloufar Najjar led data collection, data analysis, and preparation of the manuscript. Nastaran Hadizadeh contributed to the preparation of the manuscript and participated in critical review. Parvin Pasalar1 and Farideh Razi played key roles in the planning, implementation, and management of the study. Babak Arjmand and Fatemeh Bandarian participated in the study design, helped to refine data-collection tools, and assisted in managing data collection.
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The study was approved by the Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences.
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Hosseinkhani, S., Arjmand, B., Bandarian, F. et al. Omics experiments in Iran, a review in endocrine and metabolism disorders studies. J Diabetes Metab Disord (2021). https://doi.org/10.1007/s40200-021-00727-0
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DOI: https://doi.org/10.1007/s40200-021-00727-0