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Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review

  • Review article
  • Published:
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Abstract

Objectives

Fruit vinegar is one of the most famous fruit byproducts worldwide with several unique properties. There are two types of fruit vinegar, artisanal and industrial, for consumers to choose from. This review aims to assess for the first time the phytochemistry of fruit vinegar and its anti-inflammatory effects.

Method

The present work was conducted based on a literature search that selected the relevant papers from indexed databases such as Scopus, Science Direct, MDPI, PubMed, Hindawi, and Web of Science. We used numerous terms to assure a good search in different databases, including fruit vinegar, phytochemistry, bioavailability and bioaccessibility, and anti-inflammatory effect. All articles were selected based on their relevance, quality, and problematic treatment.

Results

Literature data have shown that vinegar has a long medicinal history and has been widely used by different civilizations, due to its richness in bioactive molecules, vinegar plays an important role in the prevention and treatment of various inflammatory diseases, including atopic dermatitis, mastitis, asthma, arthritis, acute pancreatitis, and colitis. Fruit vinegar consumption benefit is highly dependent on its chemical composition, especially organic acids and antioxidants, which can act as nutraceuticals.

Conclusion

Fruit vinegar has a rich chemical composition, including organic acids that can be transformed in the digestive system into compounds that play an important role in health-promoting features such as anti-inflammatory effects throughout the control of intestinal microbiota and pro-inflammatory cytokine production.

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Data Availability

The data used to support the findings of this study are included within the article.

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  1. Laboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of Life (SNAMOPEQ), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University, Fez, 30000, Morocco

    Driss Ousaaid, Meryem Bakour, Hassan Laaroussi, Asmae El Ghouizi, Badiaa Lyoussi & Ilham El Arabi

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  1. Driss Ousaaid
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Conceptualization and writing original draft-review: Driss OUSAAID; writing, review, and editing: Meryem BAKOUR, Hassan LAAROUSSI, Asmae EL GHOUIZI; supervision: Badiaa LYOUSI and Ilham EL ARABI.

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Ousaaid, D., Bakour, M., Laaroussi, H. et al. Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review. DARU J Pharm Sci (2023). https://doi.org/10.1007/s40199-023-00493-9

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