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Primary Endoscopic Treatments for Obesity

  • Bariatric Surgery (A Ghaferi, Section Editor)
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Abstract

Purpose of the review

Endoscopic bariatric therapies (EBTs) are suitable alternatives since only a tiny portion of patients with definite indications undergo bariatric surgery. Several endoluminal modalities are currently available, but the level of evidence supporting each of them varies widely. This review aims to summarize the most relevant and novel evidence on EBTs.

Recent findings

The intragastric balloon is the oldest EBT, and there is sound evidence supporting its use to address overweight and obesity; there is a novel space-occupying device that causes intermittent gastric outlet obstruction and has recently been approved by the FDA; gastric reduction methods (POSE and Endoscopic Sleeve Gastroplasty) have new and promising data showing its effectiveness and safety; the endoluminal duodenal bypass liner has been abandoned from clinical use due to high rates of serious adverse events.

Summary

This article reviews the novel and traditional EBTs and their corresponding supportive data for the primary treatment of obesity. Also, we provide insightful personal perspectives on the future of endoluminal bariatric therapies.

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Authors and Affiliations

  1. Gastrointestinal Endoscopy Unit, Gastroenterology Department, University of São Paulo Medical School, Eneas de Carvalho Aguiar Av. 255, São Paulo, São Paulo, Brazil

    Vitor Ottoboni Brunaldi

  2. Center for Gastrointestinal Endoscopy, Surgery and Anatomy Department, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Prêto, Brazil

    Vitor Ottoboni Brunaldi

  3. Surgery Department, Florida International University, Miami, FL, USA

    Manoel Galvao Neto

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  1. Vitor Ottoboni Brunaldi
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Correspondence to Vitor Ottoboni Brunaldi.

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VOB declare no conflicts of interest. MGN reports personal fees from APOLLO ENDOSURGERY, personal fees from COLUBRIS MX, personal fees from GY DYNAMICS, personal fees from FRACTYL LABS, non-financial support from M.I.TECH, personal fees from KEYRON, personal fees from MEDTRONICS, and personal fees from APSEN, outside the submitted work.

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Brunaldi, V.O., Galvao Neto, M. Primary Endoscopic Treatments for Obesity. Curr Surg Rep 9, 12 (2021). https://doi.org/10.1007/s40137-021-00291-9

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