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Headache and cerebral venous sinus thrombosis as a first presentation of mixed connective tissue disease: a rare case and literature review

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Fig. 1

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Patient data will be anonymized to protect the privacy of the participants.

Abbreviations

ANCA:

Antineutrophilic cytoplasmic antibody

CTD:

Connective tissue disease

CVT:

Cerebral venous thrombosis

FLAIR:

Fluid-attenuated inversion recovery

MCTD:

Mixed connective tissue disorder

MRI:

Magnetic resonance imaging

MTHFR:

Methylenetetrahydrofolate reductase

Anti-SSA:

Autoantibodies anti-sjogren-syndrome-related-antigen A antibodies

U1RNP:

Anti-U1-ribonucleoprotein

References

  1. Sharp GC, Irvin WS, Tan EM, Gould RG, Holman HR. (1972) Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med [Internet]. Feb [cited 2023 Oct 27];52(2):148–59. https://linkinghub.elsevier.com/retrieve/pii/0002934372900642

  2. John KJ, Sadiq M, George T, Gunasekaran K, Francis N, Rajadurai E, et al. (2020) Clinical and immunological profile of mixed connective tissue disease and a comparison of four diagnostic criteria. Int J Rheumatol [Internet]. Jan 29 [cited 2023 Oct 27];2020:1–6. https://www.hindawi.com/journals/ijr/2020/9692030/

  3. Springer J, Villa-Forte A. (2013) Thrombosis in vasculitis. Curr Opin Rheumatol [Internet]. [cited 2024 Jan 22];25(1):19–25. https://journals.lww.com/00002281-201301000-00006

  4. Shah PM, Dhakre VW, Bhabhor A, Prasad A (2018) Superior sagittal sinus thrombosis in a case of mixed connective tissue disease. BMJ Case Rep. https://doi.org/10.1136/bcr-2018-225078

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Acknowledgements

I acknowledge the help of all my colleagues, nursing staff, and supporting team.

Funding

The authors declare that they did not receive funding from any source.

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Authors and Affiliations

  1. Department of Neurology, DKSPGI (Dau Kalyan Singh Postgraduate Institute), OPD Room No 05, Ground Floor, Raipur, Chhattisgarh, 492001, India

    Arpit Agrawal & Abhijeet Kumar Kohat

  2. Department of Radiology, PTJNMMC (Pandit Jawahar Lal Nehru Memorial Medical College), Raipur, Chhattisgarh, India

    Chandradev Sahu

  3. Department of Pathology, All India Institute of Medical Sciences (AIIMS, Raipur), Raipur, Chhattisgarh, India

    Chitrakshi Kansal

  4. PTJNMMC (Pandit Jawahar Lal Nehru Memorial Medical College), Raipur, Chhattisgarh, India

    Anam Fatima

Authors
  1. Arpit Agrawal
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  2. Abhijeet Kumar Kohat
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  3. Chandradev Sahu
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  4. Chitrakshi Kansal
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  5. Anam Fatima
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Contributions

Design and conceptualization of the study: AA, AKK. Analysis/interpretation of the data: CDS, AA, AKK. Drafting and revising the manuscript; AA, CK, AF. Acquiring the data and revising the manuscript for intellectual content; all authors. All authors read and approved the final manuscript.

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Correspondence to Arpit Agrawal.

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The authors declare that they have no competing interests.

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The institutional review board does not require ethics approval for case reports.

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Written informed consent was obtained from the patient.

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Agrawal, A., Kohat, A.K., Sahu, C. et al. Headache and cerebral venous sinus thrombosis as a first presentation of mixed connective tissue disease: a rare case and literature review. Acta Neurol Belg (2024). https://doi.org/10.1007/s13760-024-02548-3

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