Skip to main content

Advertisement

Log in

Antimicrobial stewardship in pediatrics: An Indian perspective

  • Special Article
  • Published:
Indian Pediatrics Aims and scope Submit manuscript

Abstract

Antimicrobial resistance has become a global menace. As the resistance patterns and numbers are progressively increasing, it has become a major cause of morbidity and mortality in hospitalized patients, especially children. Efforts are being put world-over to curb the rising resistance by various means, especially by promoting Antibiotic Stewardship Program. These are cluster of interventions targeted towards the improvement and monitoring of appropriate antimicrobial use by selecting the most optimal drug regimen, including the type of drug used, the dose, the duration of therapy and the route of administration. India has also been working consistently to control antibiotic resistance and promote implementation of antibiotic stewardship program. Although the success rates are yet not very high, due to lot of barriers, but it is important to take measures to overcome the barriers and curb the rising resistance at the earliest.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Centre for Disease Control and Prevention. Core Elements of Hospital Antibiotic Stewardship Programs. Atlanta, GA: US Department of Health and Human Services, CDC; 2014. Available From: http://www.cdc.gov/getsmart/ healthcare/pdfs/core-elements.pdf. Accessed July 1, 2015.

  2. World Health Organization. The WHO policy package to combat antimicrobial resistance. Bull World Health Organ. 2011. Available http://www.who.int/bulletin/volumes/89/ 5/11-088435.pdf. Accessed July 1, 2015.

  3. Indian Network for Surveillance of Antimicrobial Resistance (INSAR) Group, India. Methicillin resistant Staphylococcus aureus (MRSA) in India: Prevalence & susceptibility pattern. Indian J Med Res. 2013;137:363–9.

    Google Scholar 

  4. Kumar SG, Adithan C, Harish BN, Sujatha S, Roy G, Malini A. Antimicrobial resistance in India: A review. J Nat Sci Biol Med. 2013;4:286–91.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Lawrence R, Jeyakumar E. Antimicrobial resistance: A cause for global concern. BMC Proc. 2013:7 (Suppl 3):S1.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Yewale VN. IAP-ICMR Call to Action to tackle the antimicrobial resistance. Indian Pediatr. 2014;51:437–9.

    Article  PubMed  Google Scholar 

  7. World Health Organization. Antimicrobial resistance, fact sheet N”194. Available from: http://www.who.int/ mediacentre/factsheets/fs194/en/. Accessed September 21, 2015.

  8. Infectious diseases Society of America (IDSA). Promoting Antimicrobial Stewardship in Human Medicine. Available from: http://www.idsociety.org/stewardship_policy/. Accessed July 1, 2015.

  9. Nathwani D, Sneddon J. Practical guide to antimicrobial stewardship in hospitals. Available from: http://bsac.org.uk/wp-content/uploads/2013/07/Stewardship-Booklet-Practical-Guide-to-Antimicrobial-Stewardshipin-Hospitals.pdf. Accessed June 25, 2015.

  10. Gerber JS, Newland JG, Coffin SE, Hall M, Thurm C, Prasad PA, et al. Variability in antibiotic use at children’s hospitals. Pediatrics. 2010;126:1067–73.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Hickson M. Probiotics in the prevention of antibioticassociated diarrhoea and Clostridium difficile infection. Therap Adv Gastroenterol. 2011;4:185–197.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Nash C, Simmons E, Bhagat P, Bartlett A. Antimicrobial stewardship in the NICU: Lessons we’ve learned. Neoreviews. 2014;15:e116–22.

    Article  Google Scholar 

  13. Hyun DY, Hersh AL, Namtu K, Palazzi DL, Maples HD, Newland JG, et al. Antimicrobial stewardship in Pediatrics–How every pediatrician can be a steward. JAMA Pediatr. 2013;167:859–66.

    Article  PubMed  Google Scholar 

  14. World Health Organization. Step-by-step approach for development and implementation of hospital antibiotic policy and standard treatment guidelines. Available from: http://www.searo.who.int/entity/world_health_day/media/2011/whd-11_ha-policy.pdf. Accessed July 1, 2015.

  15. Newland JG, Gerber JS, Weissman SJ, Shah SS, Turgeon C, et al. Prevalence and characteristics of antmicrobial stewardship programs at Freestanding Children’s hospitals in the United States. Infect Control Epidemiol. 2014;35:265–71.

    Article  Google Scholar 

  16. Smith MJ, Kong M, Cambon A Woods CR. Effectiveness of Antimicrobial guidelines for community-acquired pneumonia in children. Pediatrics. 2012;129:e1326–33.

    Article  Google Scholar 

  17. Howard P, Pulcini C, Levy Hara G, West RM, Gould IM, Harbarth S, Nathwani D; ESCMID Study Group for Antimicrobial Policies (ESGAP); ISC Group on Antimicrobial Stewardship. An international crosssectional survey of antimicrobial stewardship programmes in hospitals. J Antimicrob Chemother. 2015;70:1245–55.

    CAS  PubMed  Google Scholar 

  18. Sureshkumar D, Gopalakrishnan R, Ramasubramanian V. Survey of infection control programs in India. Available from: https://idsa.confex.com/idsa/2013/webprogram/ Paper42762.html. Accessed July 1, 2015.

  19. Global Antibiotic Resistance Partnership (GARP) -India Working Group. Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res. 2011;134:281–94.

    PubMed Central  Google Scholar 

  20. National Policy for Containment of Antimicrobial Resistance; Directorate General of Health Services, Ministry of Health and Family Welfare, 2011. Available from: http://www.mohfw.nic.in/showfile.php?lid=2727. Accessed June 10, 2015.

  21. Chennai Declaration Team. The Chennai Declaration: Recommendations of a roadmap to tackle the challenge of antimicrobial resistance. A Joint Meeting of Medical Societies of India. Indian J Cancer. 2012;49:84–94.

    Google Scholar 

  22. Chandy SJ, Michael JS, Veeraraghavan B, Abraham OC, Bachhav SS, Kshirsagar NA. ICMR program on antibiotic stewardship, prevention of infection and control (ASPIC). Indian J Med Res. 2014;139:226–30.

    PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Piyush Gupta.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bedi, N., Gupta, P. Antimicrobial stewardship in pediatrics: An Indian perspective. Indian Pediatr 53, 293–298 (2016). https://doi.org/10.1007/s13312-016-0839-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-016-0839-7

Keywords

Navigation