Abstract
Background
Studies of prophylactic salpingo-oophorectomies in high-risk population led to incidental finding of precursor lesions in the fimbrial end of fallopian tube rather than the ovary. Early detection of these precursor lesions can be helpful in the prevention of ovarian tumors, and the presence of these lesions can be more efficiently studied by applying Sectioning and Extensively Examining the FIMbriated End (SEE-FIM) protocol.
Aim
To study precursor lesions of fallopian tubes associated with ovarian tumors by applying SEE-FIM protocol.
Materials and methods
Sixty specimens of hysterectomy with bilateral salpingo-oophorectomy, clinically diagnosed as ovarian tumor (study group), were examined by SEE-FIM protocol. Specimens without ovarian tumor were taken as the control group, and same protocol was applied on them. Histological changes in fallopian tube were grouped either as tubal intraepithelial carcinoma (TIC), tubal intraepithelial lesion (TIL), only stratification and negative for any changes.
Results
Out of 60 cases in the study group, 10.00% (6/60) cases showed TIC, 38.34% (23/60) cases revealed TIL, 23.33% (14/60) cases showed changes of stratification and the rest were negative for any changes. Among these 60 cases, there were 7 cases of high-grade serous carcinoma, 5 (71.43%) of them showed changes of TIC. In the control group, out of 60 cases, none showed TIC changes, TIL was noted in 6.66% (4/60) cases, changes of stratification were seen in 26.67% (16/60) cases and the rest were negative for any changes.
Conclusion
SEE-FIM protocol maximizes the examination of fimbrial end and is helpful in identifying precursor lesions of ovarian epithelial tumors.
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This is a research involving human participants. Ethical clearance certification was taken from the authorized body.
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Dr. Swati Arora is a Post-Graduate, Dr. B. R. Yelikar is a Professor and H.O.D, Dr. Mahesh H. Karigoudar is a Professor. All the authors belong to Department of Pathology, BLDEU’S Shri B.M Patil Medical College, Hospital and Research Centre, Vijayapur, Karnataka.
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Arora, S., Yelikar, B.R. & Karigoudar, M.H. Evaluation of SEE-FIM (Sectioning and Extensively Examining the FIMbriated End) Protocol in Identifying Fallopian Tube Precursor Lesions in Women with Ovarian Tumors. J Obstet Gynecol India 69 (Suppl 2), 153–159 (2019). https://doi.org/10.1007/s13224-018-1155-z
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DOI: https://doi.org/10.1007/s13224-018-1155-z