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Annotating the Role of 18F-FDG PET/CT in Fibromatoses: A Benign Masquerader of Malignancies—Is It Really an Advantageous Tool?

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Abstract

Fibromatoses are a heterogeneous group of benign proliferating fibroblasts and myofibroblasts which have a high predilection for recurrence and local invasion, especially deep fibromatoses or desmoid fibromatosis. 18F-FDG PET/CT, the workhorse of oncological imaging in nuclear medicine, can be employed to figure out the nature and aggressiveness of the lesions and various sites of involvement and to monitor treatment response to systemic therapies like tyrosine kinase inhibitors in case of deep or desmoid fibromatoses which is shown in the current research work.

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Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.

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Authors and Affiliations

  1. Department of Nuclear Medicine and PET/CT, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India

    Srinivas Ananth Kumar, Harmandeep Singh & Bhagwant Rai Mittal

  2. Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India

    Lileswar Kaman

  3. Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

    Ritambhra Nada

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  1. Srinivas Ananth Kumar
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  2. Harmandeep Singh
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  3. Lileswar Kaman
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  4. Ritambhra Nada
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  5. Bhagwant Rai Mittal
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Contributions

Srinivas Ananth Kumar participated in the study design, drafting of the manuscript, and data acquisition. Harmandeep Singh, Lileswar Kaman, Ritambhra Nada, and Bhagwant Rai Mittal participated in the study conception and design, manuscript revision, and approval of the final content of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Harmandeep Singh.

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Ethics Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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The institutional review board of our institute approved this study, and the requirement to obtain informed consent was waived.

Conflict of Interest

Srinivas Ananth Kumar, Harmandeep Singh, Lileswar Kaman, Ritambhra Nada, and Bhagwant Rai Mittal declare no competing interests.

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Kumar, S.A., Singh, H., Kaman, L. et al. Annotating the Role of 18F-FDG PET/CT in Fibromatoses: A Benign Masquerader of Malignancies—Is It Really an Advantageous Tool?. Nucl Med Mol Imaging 58, 140–146 (2024). https://doi.org/10.1007/s13139-024-00846-5

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  • DOI: https://doi.org/10.1007/s13139-024-00846-5

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