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Does anticoagulation therapy prevent thrombosis in coronary stent grafts?

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Abstract

A polytetrafluoroethylene (PTFE)-covered stent was deployed for enlarging coronary aneurysms in a 73-year-old man. Optical coherence tomography (OCT) and coronary angioscopy performed 3 months later revealed naked stent struts and thin patches of red thrombi covering the PTFE membrane even under dual antiplatelet therapy (DAPT). After 5-month warfarin administration under DAPT, OCT and angioscopy showed a clear extinction of the thin patches of red thrombi on the PTFE membrane and stent struts, although most of the struts were still naked. The addition of anticoagulation therapy to DAPT may reduce thrombosis events in patients treated with PTFE-covered stents.

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Authors and Affiliations

  1. Division of Cardiology, Fuji Hospital, Shizuoka, Japan

    Yuki Honda

  2. Division of Cardiology, Department of Internal Medicine, Showa University Koto-Toyosu Hospital, 5-1-38 Toyosu, Koto-ku, Tokyo, 135-8577, Japan

    Kohei Wakabayashi

  3. Division of Cardiovascular Surgery, Fuji Hospital, Shizuoka, Japan

    Takayasu Suzuki

  4. Division of Cardiology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan

    Hiroshi Suzuki

Authors
  1. Yuki Honda
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  2. Kohei Wakabayashi
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  3. Takayasu Suzuki
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  4. Hiroshi Suzuki
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Corresponding author

Correspondence to Kohei Wakabayashi.

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None of the authors has any potential financial conflict of interest related to this manuscript.

Ethics

The present study was approved by the ethics committee at each participating site and was conducted in accordance with the Declaration of Helsinki.

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Honda, Y., Wakabayashi, K., Suzuki, T. et al. Does anticoagulation therapy prevent thrombosis in coronary stent grafts?. Cardiovasc Interv and Ther 32, 405–408 (2017). https://doi.org/10.1007/s12928-016-0443-8

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  • DOI: https://doi.org/10.1007/s12928-016-0443-8

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