Skip to main content

Advertisement

SpringerLink
Log in

Surgical Excision of Keloid in the Ear Lobule and Reconstruction with Full-Thickness Graft followed by Injection of PRP and Hyaluronic Acid—A Case Report

  • CASE REPORT
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

References

  1. Dong X, Mao S, Wen H (2013) Upregulation of proinflammatory genes in skin lesions may be the cause of keloid formation (review). Biomed Rep [Internet] Spandidos Publ 1:833–836. https://doi.org/10.3892/br.2013.169/abstract

    Article  CAS  Google Scholar 

  2. Hunasgi S, Koneru A, Vanishree M, Shamala R (2013) Keloid: a case report and review of pathophysiology and differences between keloid and hypertrophic scars. J Oral Maxillofac Pathol [Internet] 17:116–120. https://doi.org/10.4103/0973-029X.110701

    Article  PubMed  Google Scholar 

  3. Huang C, Liu L, You Z, Du Y, Ogawa R (2019) Managing keloid scars: from radiation therapy to actual and potential drug deliveries. Int Wound J [Internet] 16:852–859. https://doi.org/10.1111/iwj.13104

    Article  PubMed  Google Scholar 

  4. Lee JY-Y, Yang C-C, Chao S-C, Wong T-W (2004) Histopathological differential diagnosis of keloid and hypertrophic scar. Am J Dermatopathol Internet 26:379. https://journals.lww.com/amjdermatopathology/Abstract/2004/10000/Histopathological_Differential_Diagnosis_of_Keloid.6.aspx

  5. Alser OH, Goutos I (2018) The evidence behind the use of platelet-rich plasma (PRP) in scar management: a literature review. Scars Burn Heal [Internet] 4:2059513118808773. https://doi.org/10.1177/2059513118808773

    Article  PubMed  Google Scholar 

  6. Elsaie ML (2021) Update on management of keloid and hypertrophic scars: a systemic review. J Cosmet Dermatol [Internet] 20:2729–2738. https://doi.org/10.1111/jocd.14310

    Article  PubMed  Google Scholar 

  7. Tedeschi A, Lacarrubba F, Micali G (2015) Mesotherapy with an intradermal hyaluronic acid formulation for skin rejuvenation: an intrapatient, placebo-controlled, long-term trial using high-frequency ultrasound. Aesthet Plast Surg [Internet] 39:129–133. https://doi.org/10.1007/s00266-014-0432-1

    Article  Google Scholar 

  8. De Angelis B, D’Autilio MFLM, Orlandi F, Pepe G, Garcovich S, Scioli MG, et al. (2019) Wound healing: in vitro and in vivo evaluation of a bio-functionalized scaffold based on hyaluronic acid and platelet-rich plasma in chronic ulcers. J Clin Med Res [Internet]. https://doi.org/10.3390/jcm8091486

  9. Hewedy E-SS, Sabaa BE-SI, Mohamed WS, Hegab DS (2022) Combined intralesional triamcinolone acetonide and platelet rich plasma versus intralesional triamcinolone acetonide alone in treatment of keloids. J Dermatolog Treat [Internet] 33:150–156. https://doi.org/10.1080/09546634.2020.1730742

    Article  CAS  PubMed  Google Scholar 

  10. DI Stadio A (2016) Ear keloid treated with infiltrated non-cross-linked hyaluronic acid and cortisone therapy. In Vivo [Internet] 30:695–699. https://www.ncbi.nlm.nih.gov/pubmed/27566093

  11. Park TH, Park JH, Chang CH (2014) Analysis of surgical treatments for earlobe keloids: analysis of 174 lesions in 145 patients [Internet]. Plast Reconstr Surg. https://doi.org/10.1097/PRS.0000000000000136

  12. Ogawa R (2022) The most current algorithms for the treatment and prevention of hypertrophic scars and keloids: a 2020 update of the algorithms published 10 years ago. Plast Reconstr Surg [Internet] 149:79e–94e. https://doi.org/10.1097/PRS.0000000000008667

Download references

Acknowledgements

We thank Saveetha Institute of Medical and Technical Sciences for their support in conducting this study.

Funding

This work was supported in part by Saveetha Institute of Medical and Technical Sciences.

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600077, India

    Rubin S. John & M. Senthil Murugan

  2. Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600077, India

    P. E. Jai Rexlin

Authors
  1. Rubin S. John
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. E. Jai Rexlin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Senthil Murugan
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Rubin S John designed the study, provided the materials, and supervised the study; P.E. Jai Rexlin wrote the manuscript, and Rubin S. John and M. Senthil Murugan did the final critical revision of the article.

Corresponding author

Correspondence to Rubin S. John.

Ethics declarations

Conflict of Interest

The authors declare that there are no relevant conflicts of interest.

Ethical Approval

The study involving the human participant was reviewed and approved by Institutional Human Ethics Committee [Approval Number: IHEC/SDC/UG-1833/22/OMFS/560].

Consent to Participate

The patient provided his written informed consent to participate in this study.

Consent for Publication

The patient provided his written informed consent to participate in this study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

John, R.S., Rexlin, P.E.J. & Murugan, M.S. Surgical Excision of Keloid in the Ear Lobule and Reconstruction with Full-Thickness Graft followed by Injection of PRP and Hyaluronic Acid—A Case Report. J. Maxillofac. Oral Surg. 22 (Suppl 1), 168–172 (2023). https://doi.org/10.1007/s12663-023-01877-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-023-01877-9

Search

Navigation