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Comparative Study on the Efficacy of Postsurgical Oral Prophylactic Antibiotic Versus Antimicrobial Suture Placement Alone in Preventing Surgical Site Infection After Removal of Impacted Mandibular Third Molar

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Abstract

Aim

To evaluate the efficacy of postsurgical oral prophylactic antibiotic versus antimicrobial suture placement in preventing infection after removal of an impacted mandibular third molar.

Materials and methods

This was a prospective, single-blind study including 150 individuals of 18–40 years divided into two groups with 75 patients each. The patients in Group 1 were administered oral amoxicillin tablets 500 mg for 5 days postsurgery with 3–0 polyglactin sutures for closure and in group 2 with (3–0) antimicrobial chlorhexidine diacetate-impregnated polyglactin sutures only. Evaluation was done on 3rd, 7th, 15th days and 1 month.

Results

There was no significant difference in rates of infection between the groups. Abnormal erythema, pain and trismus showed statistically better results in group 2 on 3rd and 7th days. An antibiotic side effect assessment showed 17.65% patients with minor side effects.

Conclusion

Chlorhexidine diacetate-impregnated polyglactin sutures showed reduced erythema, pain and trismus in healthy patients undergoing surgical removal of third molar.

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Acknowledgements

The author would like to express their sincere gratitude to Dr. Vinod Thangaswamy, Professor and Head of the Department of Coorg Institute of Dental Sciences.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India

    Shama Mohan, B. S. Jayanth, Shruthi Saralaya, S. M. Sunil, A. S. Mohamed Sageer & R. Harikrishnan

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  1. Shama Mohan
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  2. B. S. Jayanth
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  3. Shruthi Saralaya
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  4. S. M. Sunil
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  5. A. S. Mohamed Sageer
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  6. R. Harikrishnan
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Correspondence to Shama Mohan.

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Informed consent was obtained from all individual participants included in the study.

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Mohan, S., Jayanth, B.S., Saralaya, S. et al. Comparative Study on the Efficacy of Postsurgical Oral Prophylactic Antibiotic Versus Antimicrobial Suture Placement Alone in Preventing Surgical Site Infection After Removal of Impacted Mandibular Third Molar. J. Maxillofac. Oral Surg. 19, 546–551 (2020). https://doi.org/10.1007/s12663-019-01267-0

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  • DOI: https://doi.org/10.1007/s12663-019-01267-0

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