Abstract
This study aimed to prepare a resin based dental sealant loaded with novel bioactive glass formulated from (50 wt% calcium silicate and 50 wt% sodium silicate) with different percentages of fluorapatite. Four glass batches were formulated then characterized using Fourier Transform Infrared Spectroscopy analysis, X-ray powder diffraction analysis and Transmission electron microscopy. Density, microhardness and bioactivity testing after insertion in artificial saliva were done. Four bisphenol A-glycidyl methacrylate (Bis-GMA) based sealants loaded with the glass batch that showed the preeminent properties and silica fillers were prepared. The prepared sealants were compared to commercial sealants regarding flow, curing depth, compressive strength and microhardness. Sealant composition that showed comparable properties to that of the commercial sealant was selected for pH changes and ion release testing after immersion in artificial saliva for different time intervals. Results indicated amorphous nature, bioactive behavior and apatite forming ability of the tested glass batches. Experimental sealant revealed comparable tested properties with lower compressive strength compared to the commercial sealants at P < 0.001. The mean pH values of the tested sealants ranged from 6.75 to 6.35 with extended calcium and phosphorus ion release up to 90 days. It was concluded that the 85 wt% calcium silicate and sodium silicate with 15 wt% fluorapatite had the best trend regarding ion release and apatite forming ability. Sealant loaded with 65 wt% bioactive glass, 10 wt% sintered nanosilica and 10 wt% nanosilica had the best acceptable mechanical properties. The novel pit and fissure sealant is a promising bioactive and ion releasing material.
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Acknowledgements
Thanks are due to the National Research Centre for allowing the use of the Dental materials laboratory facilities and their financial support, grant number; 12060206.
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Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB). The authors disclosed receipt of the following financial support for the research, authorship of this article: The authors acknowledge National Research Centre in Egypt for funding the published work through project no. 12060206 entitled “Synthesis and In Vitro Characterization of Bioactive Glass-based Pit and Fissure Sealant for Caries Prevention”.
Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB).
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Engie M. Safwat: Conceptualization, Investigation, Yasmine M. Alkabani: Data curation Methodology, Dalia Y. Zaki: Writing- Original draft preparation, Mai M. Elbatanony: Methodology, Investigation. A. G. Abd-Elsatar: Software, Investigation, Reham S. Saleh Validation, Investigation, Gamal A. Khater: Supervision, Methodology, Investigation. All authors: Writing- Reviewing and Editing.
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Safwat, E.M., Alkabani, Y.M., Zaki, D.Y. et al. Preparation and Characterization of Dental Pit and Fissure Sealant Based on Calcium Sodium Silicate Bioactive Glasses. Silicon 15, 6785–6800 (2023). https://doi.org/10.1007/s12633-023-02517-0
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DOI: https://doi.org/10.1007/s12633-023-02517-0