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Facile synthesis of CuO–Co3O4 prickly-sphere-like composite for non-enzymatic glucose sensors

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Abstract

In the field of glucose sensors, the development of inexpensive and high-efficiency electrochemical glucose sensors is the current research hotspot. In this paper, CuO–Co3O4 composite with a prickly-sphere-like morphology is prepared by the facile hydrothermal method for the non-enzymatic electrochemical glucose detection. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy are used to analyze the structure, composition, and morphology of the material. In addition, the electrochemical catalytic performance of CuO–Co3O4 to glucose is obtained by cyclic voltammetry and chronoamperometry. The excellent electrochemical sensing performance may be attributed to the large number of catalytic sites in the prickly-sphere-like composite and the synergistic effect of Cu and Co. Under an applied voltage of 0.55 V, CuO–Co3O4 composite shows sensitivity to glucose (1503.45 μA·(mmol·L−1)−1·cm−2), a low detection limit (21.95 μmol·L−1), excellent selectivity, a high level of reproducibility, and good stability. This indicates that the CuO–Co3O4 composite has a broad prospect of non-enzymatic glucose sensing application.

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摘要

在葡萄糖传感器领域, 开发廉价高效的电化学葡萄糖传感器是当前的研究热点。本文采用简便的水热法制备了具有多刺球形形貌的CuO–Co3O4复合材料, 用于非酶电化学葡萄糖检测。X射线衍射(XRD)、扫描电子显微镜(SEM)、透射电子显微镜(TEM)、能量色散X射线光谱(EDX)和X射线光电子光谱(XPS)用于分析材料的结构、成分和形态。此外, 通过循环伏安法和计时电流法研究了CuO–Co3O4对葡萄糖的电化学催化性能。优异的电化学传感性能可能归因于多刺球形复合物中的大量催化位点以及铜和钴的协同作用。在0.55伏的外加电压下, CuO–Co3O4复合物显示出对葡萄糖的灵敏度(1503.45 μA·mM-1·cm-2)、低检测限(21.95 μM)、优异的选择性、高水平的再现性和良好的稳定性。这表明CuO–Co3O4复合材料在非酶葡萄糖传感领域具有广阔的应用前景。

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Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (Nos. 62074018 and 62174015), the Developing Project of Science and Technology of Jilin Province (No. 20200301052RQ), the Project of Education Department of Jilin Province (No. JJKH20210831KJ) and the Science and Technology Foundation of State Grid Corporation of China (No. SGTJDK00DYJS2000148).

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Authors and Affiliations

  1. School of Chemical Engineering, Northeast Electric Power University, Jilin, 132012, China

    Dong Wang, Hua-Min Zhao, Long Zhang, Sheng Li & Gong Wang

  2. Department of Nursing, Changchun People’s Hospital, Changchun, 130000, China

    Li Guo

  3. State Key Laboratory of Advanced Materials for Smart Sensing, General Research Institute for Nonferrous Metals, Beijing, 100088, China

    Hong-Bin Zhao

  4. State Key Laboratory of High Power Semiconductor Lasers, School of Science, Changchun University of Science and Technology, Changchun, 130022, China

    Xuan Fang

  5. School of Automation Engineering, Northeast Electric Power University, Jilin, 132000, China

    Sheng Li & Gong Wang

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  1. Dong Wang
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Wang, D., Zhao, HM., Guo, L. et al. Facile synthesis of CuO–Co3O4 prickly-sphere-like composite for non-enzymatic glucose sensors. Rare Met. 41, 1911–1920 (2022). https://doi.org/10.1007/s12598-021-01939-2

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  • DOI: https://doi.org/10.1007/s12598-021-01939-2

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