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Het STIPP-onderzoek

Een RCT naar het effect van een vroeginterventie bij zeer vroeg geboren kinderen op de ontwikkeling van het kind, het welbevinden van de ouder en de ouder-kindinteractie

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Tijdschrift voor Kindergeneeskunde

Samenvatting

Doel

Onderzoeken van het effect van het Infant Behavioral Assessment and Intervention Program© (IBAIP) op de ontwikkeling van zeer vroeg geboren kinderen, het welbevinden van de ouder en de ouder-kindinteractie.

Methode

In een multicenter gerandomiseerde gecontroleerde studie kregen 86 te vroeg geboren kinderen (zwangerschapsduur < 32 weken en/of een geboortegewicht < 1500 g) thuisbegeleiding tot de gecorrigeerde leeftijd van 6 maanden en 90 kinderen kregen standaardzorg. Op de gecorrigeerde leeftijd van 6, 12, 18 en 24 maanden en 3,7 en 5,5 jaar werden de ontwikkeling van het kind en/of het welbevinden van de ouder en de ouder-kindinteractie onderzocht.

Resultaten

De interventiegroep had significant betere scores op cognitie op 6 maanden en 5,5 jaar, op motoriek op 6, 12 en 24 maanden, 3,7 en 5,5 jaar en op gedrag op 6 en 12 maanden. De moeders in de interventiegroep waren sensitiever op 6 maanden en hadden minder opvoedkundige stress op 24 maanden. Er was geen interventie-effect op het psychisch welbevinden van de moeder, maar het welbevinden verbeterde wel over de tijd.

Conclusie

Het IBAIP leidt tot meer sensitieve moeder-kindinteracties en heeft een positief effect op de ontwikkeling van het kind. Verbetering van de motorische ontwikkeling hield aan en 5 jaar na de interventie was er opnieuw verbetering van de cognitieve ontwikkeling, vooral van de performale vaardigheden. De ervaringen uit deze studie hebben geleid tot implementatie van een preventief interventieprogramma voor vroeg geboren kinderen in Nederland, het ToP-programma (Transmurale Ontwikkelingsondersteuning voor Prematuur geboren kinderen en hun ouders).

Summary

Aim.

To assess the effect of the Infant Behavioral Assessment and Intervention Program© (IBAIP) on the development of the very preterm infant, the wellbeing of the parent, and the parentchild interaction.

Method.

In a multicentre randomized controlled trial, 86 preterm infants (born < 32 weeks gestation and/or < 1500 g birth weight) received intervention at home, until 6 months corrected age, and 90 infants received usual care. At the corrected age of 6, 12, 18 and 24 months, and at 3.7 and 5.5 years, the development of the child, the wellbeing of the mothers, and the mother-child interaction were assessed.

Results.

The intervention group had significantly better scores on cognition at 6 months and 5.5 years, on motor function at 6, 12, 24 months and 3.7 and 5.5 years and on behaviour at 6 and 12 months. The mothers in the intervention group had increased maternal sensitivity at 6 months and decreased parenting stress at 24 months. No effect of the intervention was found for the psychological wellbeing of the mother, but their wellbeing improved over time.

Conclusion.

IBAIP has a positive effect on maternal sensitivity and the development of the child. The intervention showed sustained improvement of motor function, and 5 years after ending the intervention improvement of cognitive development reappeared, especially performance skills. Taken together, the outcomes of this study have resulted in the implementation of a preventive intervention programme for preterm infants in the Netherlands: the ToP programme (Transmurale Ontwikkelingsondersteuning voor Prematuur geboren kinderen en hun ouders).

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Author information

Authors and Affiliations

  1. afdeling Revalidatie, AMC, 22660, 1100, DD, Amsterdam, The Netherlands

    Martine Jeukens-Visser,  J.W.P. van Hus,  Karen Koldewijn,  Dominique Meijssen,  Gijs Verkerk &  Frans Nollet

  2. afdeling Neonatologie, Emma Kinderziekenhuis, AMC, Amsterdam, The Netherlands

    Aleid G. van Wassenaer-Leemhuis &  Joke Kok

  3. Child and Adolescent Studies, Universiteit van Utrecht, Utrecht, The Netherlands

    Anneloes van Baar

  4. afdeling Revalidatie en Neonatologie, AMC, Amsterdam, The Netherlands

    Marie Jeanne Wolf

Authors
  1. Martine Jeukens-Visser
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  2. J.W.P. van Hus
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  3. Karen Koldewijn
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  4. Dominique Meijssen
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  5. Gijs Verkerk
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  6. Frans Nollet
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  7. Aleid G. van Wassenaer-Leemhuis
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  8. Anneloes van Baar
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  9. Joke Kok
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  10. Marie Jeanne Wolf
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Corresponding author

Correspondence to J.W.P. van Hus.

Additional information

Mw. dr. Martine Jeukens-Visser en mw. Janeline W.P. van Hus, BSc (beide auteurs zijn eerste auteur), mw. dr. Karen Koldewijn, mw. dr. Dominique Meijssen, dhr. dr. Gijs Verkerk, en dhr. prof. dr. Frans Nollet, afdeling Revalidatie, AMC, Amsterdam. Mw. dr. Aleid G. van Wassenaer-Leemhuis, afdeling Neonatologie, Emma Kinderziekenhuis, AMC, Amsterdam. Mw. prof. dr. Anneloes van Baar, Child and Adolescent Studies, Universiteit van Utrecht. Mw. prof. dr. Joke Kok, afdeling Neonatologie, Emma Kinderziekenhuis, AMC, Amsterdam. Mw. dr. Marie Jeanne Wolf, afdeling Revalidatie en Neonatologie, AMC, Amsterdam.

Correspondentieadres: Janeline W.P. van Hus, afdeling Revalidatie, AMC, Postbus 22660, 1100 DD Amsterdam, J.W.vanhus@amc.uva.nl.

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Jeukens-Visser, M., van Hus, J., Koldewijn, K. et al. Het STIPP-onderzoek. TIJDSCHR. KINDERGENEESKUNDE 82, 94–105 (2014). https://doi.org/10.1007/s12456-014-0018-5

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