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Spontaneous rupture of a hepatic angiomyolipoma: Report of a case

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Abstract

A 70-year-old female experienced sudden onset of back pain on the right side and was admitted to our hospital in December 2010. Abdominal computed tomography revealed an S7 hepatic mass measuring 7 cm in diameter accompanied by a subcapsular hematoma. Emergency angiography confirmed the diagnosis of a ruptured hepatic mass, and hemostasis was carried out by embolization of A8 and A7 of the liver. A right hepatic lobectomy was carried out 39 days following transarterial embolization. Although almost all aspects of the tumor were necrotic, residual tumor cells stained positive for HMB-45, and negative for α-SMA, S-100, CD 34, c-kit, CAM 5.2, and hepatocytes. The MIB-1 index was 2 %. Pathological diagnosis was hepatic angiomyolipoma (HAML). The patient has shown no signs of recurrence at 42 months following surgery. Here, we report on this case of spontaneous HAML rupture and discuss therapeutic strategies for HAML and ruptured hepatic tumors.

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Disclosures

Conflict of Interest:

Dr. Aoki and the co-authors have no conflicts of interest to report.

Human/Animal Rights:

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).

Informed Consent:

Informed consent was obtained from the patients for their inclusion in the study.

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Authors and Affiliations

  1. Department of Surgery, National Hospital Iwakuni Clinical Center, 1-1-1 Atago-cho, Iwakuni, Yamaguchi, 740-8510, Japan

    Hideki Aoki, Takashi Arata, Toshiaki Morihiro, Nobuhiko Kanaya, Sho Takeda, Kenta Sui, Kunitoshi Shigeyasu, Koh Katsuda, Kohji Tanakaya & Hitoshi Takeuchi

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  1. Hideki Aoki
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  2. Takashi Arata
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  3. Toshiaki Morihiro
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  4. Nobuhiko Kanaya
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  5. Sho Takeda
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  6. Kenta Sui
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  7. Kunitoshi Shigeyasu
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  8. Koh Katsuda
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  9. Kohji Tanakaya
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  10. Hitoshi Takeuchi
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Correspondence to Hideki Aoki.

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Aoki, H., Arata, T., Morihiro, T. et al. Spontaneous rupture of a hepatic angiomyolipoma: Report of a case. Clin J Gastroenterol 7, 429–433 (2014). https://doi.org/10.1007/s12328-014-0517-z

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  • DOI: https://doi.org/10.1007/s12328-014-0517-z

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