Skip to main content

Advertisement

Log in

Septicemia due to Vibrio cholerae serogroup non-O1/non-O139 strain in a cirrhotic patient

  • Case Report
  • Published:
Clinical Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

We describe a case of non-O1/ non-O139 Vibrio cholerae septicemia in a 65-year-old male patient with alcoholic liver cirrhosis. He was admitted due to septic shock from non-O1/ non-O139 V. cholerae. An intravenous empiric antibiotic, ceftriaxone sodium hydrate, was administered together with amikacin sulfate, gamma globulin and dopamine. He was discharged feeling well 17 days after admission. Poor host defense mechanisms as seen in cirrhotic patients seem to be a determinant for systemic infection of non-O1/ non-O139 V. cholerae. Such patients should be warned and educated against eating raw or undercooked seafood to avoid the occurrence of non-O1/non-O139 V. cholerae septicemia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Caly WR, Strauss E. A prospectitve study of bacterial infections in patients with cirrhosis. J Hepatol. 1993;18:353–8.

    Article  PubMed  CAS  Google Scholar 

  2. Runyon BA. Bacterial infections in patients with cirrohosis. J Hepatol. 1993;18:271–2.

    Article  PubMed  CAS  Google Scholar 

  3. Yoneyama K, Miyagishi K, Kiuchi Y, Shibata M, Mitamura K. Risk factors for infections in cirrhotic patients with and without hepatocellular carcinoma. J Gastroenterol. 2002;37(12):1028–34.

    Article  PubMed  Google Scholar 

  4. Arvaniti V, D’Amico G, Fede G, Manousou P, Tsochatzis E, Pleguezuelo M, Burroughs AK. Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis. Gastroenterology. 2010;139(4):1246–56, 1256.e1–5 (Epub 2010 Jun 14).

    Google Scholar 

  5. Restrepo D, Huprikar SS, VanHorn K, Bottone EJ. O1 and non-O1 Vibrio cholerae bacteremia produced by hemolytic strains. Diagn Microbiol Infect Dis. 2006;54:145–8.

    Article  PubMed  CAS  Google Scholar 

  6. Hlady WG, Klontz KC. The epidemiology of Vibrio infections in Florida, 1981–1993. J Infect Dis. 1996;173:1176–83.

    Article  PubMed  CAS  Google Scholar 

  7. Ko W-C, Chuang Y-C, Huang G-C, Hsu S-Y. Infections due to non-O1 Vibrio cholera in southern Taiwan: predominance in cirrhotic patients. Clin Infect Dis. 1998;27:774–80.

    Article  PubMed  CAS  Google Scholar 

  8. Halabi M, Haditsch M, Renner F, Brinniger G, Mittermayer H. Vibrio cholerae non-O1 septicaemia in a patient with liver cirrhosis and Billroth-II-gastrectomy. J Infect. 1997;34(1):83–4.

    Article  PubMed  CAS  Google Scholar 

  9. Yang CJ, Wang CS, Lu PL, Chen TC, Chen YH, Huang MS, Lin CC, Hwang JJ. Bullous cellulitis in cirrhotic patients—a rare but life-threatening infection caused by non-O1, non-O139 Vibrio cholerae bacteraemia. J Med Microbiol. 2011;60(Pt 6):861–2 (Epub 2011 Feb 3).

    Google Scholar 

  10. Petsaris O, Nousbaum JB, Quilici ML, Le Coadou G, Payan C, Abalain ML. Non-O1, non-O139 Vibrio cholerae bacteraemia in a cirrhotic patient. J Med Microbiol. 2010;59(Pt 10):1260–2 (Epub 2010 Jul 8).

    Google Scholar 

  11. Lai CC, Liu WL, Chiu YH, Chao CM, Gau SJ, Hsueh PR. Liver abscess due to non-O1 Vibrio cholerae in a cirrhotic patient with hepatocellular carcinoma. J Infect. 2011;62(3):235–7 (Epub 2011 Jan 31).

    Google Scholar 

  12. Yang CC, Lee BJ, Yang SS, Lin YH, Lee YL. A case of non-O1 and non-O139 Vibrio cholera septicemia with endophthalmitis in a cirrhotic patient. Jpn Infect Dis. 2008;61(6):475–6.

    Google Scholar 

  13. Dhar R, Ghafoor MA, Nasralah AY. Unusual non-serogroup O1 Vibrio cholerae bacteremia associated with liver disease. J Clin Microbiol. 1989;27(12):2853–5.

    PubMed  CAS  Google Scholar 

  14. Suankratay C, Phantumchinda K, Tachawiboonsak W, Wilde H. Non-serogroup O:1 Vibrio cholerae bacteremia and cerebritis. Clin Infect Dis. 2001;32(7):E117–9 (Epub 2001 Mar 20).

  15. El-Hiday AH, Khan FY, Al Maslamani M, El Shafie S. Bacteremia and spontaneous bacterial peritonitis due to Vibrio cholerae (non-O1 non-O139) in liver cirrhosis. Indian J Gastroenterol. 2006;25(2):107.

    Google Scholar 

  16. Deris ZZ, Leow VM, Wan Hassan WM, Nik Lah NA, Lee SY, Siti Hawa H, Siti Asma H, Ravichandran M. Non-O1, non-O139 Vibrio cholerae bacteraemia in splenectomised thalassaemic patient from Malaysia. Trop Biomed. 2009;26(3):320–5.

    PubMed  CAS  Google Scholar 

  17. Kadkhoda K, Adam H, Gilmour MW, Hammond GW. Nontoxigenic Vibrio cholerae septicemia in an immunocompromised patient. Case Rep Infect Dis. 2012;2012:698–746 (Epub 2012 Jul 10).

  18. Bran OS. Infectious complications of cirrhosis. Curr Gastroenterol Rep. 2001;3:285–92.

    Article  Google Scholar 

  19. Thompson FL, Iida T, Swings J. Biodiversity of vibrios. Microbiol Mol Biol Rev. 2004;68:403–31.

    Article  PubMed  CAS  Google Scholar 

  20. Namdari H, Klaips CR, Hughes JL. A cytotoxin-producing strain of Vibrio cholerae non-O1, non-O139 as a cause of cholera and bacteremia after consumption of raw clams. J Clin Microbiol. 2000;38(9):3518–9.

    PubMed  CAS  Google Scholar 

  21. Ismail EA, Shafik MH, Al-Mutairi G. A case of non-O:1 Vibrio cholerae septicemia with meningitis, cerebral abscess and unilateral hydrocephalus in a preterm baby. Eur J Clin Microbiol Infect Dis. 2001;20(8):598–600.

    Article  PubMed  CAS  Google Scholar 

  22. Berghmans T, Crokaert F, Sculier JP. Vibrio cholerae bacteremia in a neutropenic patient with non-small-cell lung carcinoma. Eur J Clin Microbiol Infect Dis. 2002;21(9):676–8 (Epub 2002 Sep 3).

    Google Scholar 

  23. Anderson AM, Varkey JB, Petti CA, Liddle RA, Frothingham R, Woods CW. Non-O1 Vibrio cholerae septicemia: case report, discussion of literature, and relevance to bioterrorism. Diagn Microbiol Infect Dis. 2004;49(4):295–7.

    Article  PubMed  Google Scholar 

  24. Strumbelj I, Prelog I, Kotar T, Dovecar D, Petras T, Socan M. A case of Vibrio cholerae non-O1, non-O139 septicaemia in Slovenia, imported from Tunisia, July 2005. Euro Surveill. 2005;10(10):E051020.6.

    Google Scholar 

  25. Stypulkowska-Misiurewicz H, Pancer K, Roszkowiak A. Two unrelated cases of septicaemia due to Vibrio cholerae non-O1, non-O139 in Poland, July and August 2006. Euro Surveill. 2006;11(11):E061130.2.

    Google Scholar 

  26. Phetsouvanh R, Nakatsu M, Arakawa E, Davong V, Vongsouvath M, Lattana O, Moore CE, Nakamura S, Newton PN. Fatal bacteremia due to immotile Vibrio cholerae serogroup O21 in Vientiane, Laos—a case report. Ann Clin Microbiol Antimicrob. 2008;25(7):10.

    Article  Google Scholar 

  27. Zárate MS, Giannico M, Colombrero C, Smayevsky J. Non-O1, non-O139 Vibrio cholerae bacteremia in a chronic hemodialysis patient. Rev Argent Microbiol. 2011;43(2):81–3 (article in Spanish).

    Google Scholar 

  28. Toeg A, Berger SA, Battat A, Hoffman M, Yust I. Vibrio cholerae bacteremia associated with gastrectomy. J Clin Microbiol. 1990;28(3):603–4.

    PubMed  CAS  Google Scholar 

  29. Patel NM, Wong M, Little E, Ramos AX, Kolli G. Vibrio cholerae non-O1 infection in cirrhotics: case report and literature review. Transpl Infect Dis. 2009;11:54–6.

    Article  PubMed  CAS  Google Scholar 

  30. Lee CH, Wang CC, Yue CT, Li KJ, Wu YK. Necrotising fasciitis caused by Vibrio vulnificus in a man with cirrhosis. Lancet Infect Dis. 2008;8(6):399.

    Article  PubMed  Google Scholar 

  31. Matsumoto K, Ohshige K, Fujita N, Tomita Y, Mitsumizo S Clinical features of Vibrio vulnificus infections in the coastal areas of the Ariake Sea, Japan. J Infect Chemother. 2010;16(4):272–9 (Epub 2010 Mar 13).

    Google Scholar 

  32. Su BA, Tang HJ, Wang YY, Liu YC, Ko WC. In vitro antimicrobial effect of cefazolin and cefotaxime combined with minocycline against Vibrio cholerae non-O1 non-O139. J Microbiol Immunol Infect. 2005;38:425–9.

    PubMed  CAS  Google Scholar 

  33. Nagao Y, Matsuoka H, Seike M, Yamasaki K, Kato J, Nakajima T, Miyazaki Y, Ohno T. Knowledge of Vibrio vulnificus infection among Japanese patients with liver diseases: a prospective multicenter study. Med Sci Monit. 2009;15(10):PH115–120.

    Google Scholar 

Download references

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masatoshi Kudo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Inoue, T., Kitai, S., Hayaishi, S. et al. Septicemia due to Vibrio cholerae serogroup non-O1/non-O139 strain in a cirrhotic patient. Clin J Gastroenterol 5, 383–387 (2012). https://doi.org/10.1007/s12328-012-0332-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12328-012-0332-3

Keywords

Navigation