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Pseudo Chediak-Higashi Granules in Acute Lymphoblastic Leukemia: A Rare Entity

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Pseudo-Chediak-Highashi granules are giant cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. They derive their name from the inherited Chediak-Higashi syndrome that presents with oculocutaneous albinism, chronic infections and platelet dense granule deficiency. We report possibly the third case in world literature where these granules were seen in the blast cells of acute lymphoblastic leukemia in a 15-year-old male.

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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Haematology, Level 5, Research Block A, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India

    Pallavi Agrawal, Narender Kumar, Prashant Sharma & Neelam Varma

  2. Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India

    Subhash Varma

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  1. Pallavi Agrawal
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  2. Narender Kumar
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  3. Prashant Sharma
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  4. Subhash Varma
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  5. Neelam Varma
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Correspondence to Narender Kumar.

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Agrawal, P., Kumar, N., Sharma, P. et al. Pseudo Chediak-Higashi Granules in Acute Lymphoblastic Leukemia: A Rare Entity. Indian J Hematol Blood Transfus 30, 201–203 (2014). https://doi.org/10.1007/s12288-012-0206-3

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  • DOI: https://doi.org/10.1007/s12288-012-0206-3

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