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Cytoplasmic molecular chaperones in Pseudomonas species

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Abstract

Pseudomonas is widespread in various environmental and host niches. To promote rejuvenation, cellular protein homeostasis must be finely tuned in response to diverse stresses, such as extremely high and low temperatures, oxidative stress, and desiccation, which can result in protein homeostasis imbalance. Molecular chaperones function as key components that aid protein folding and prevent protein denaturation. Pseudomonas, an ecologically important bacterial genus, includes human and plant pathogens as well as growth-promoting symbionts and species useful for bioremediation. In this review, we focus on protein quality control systems, particularly molecular chaperones, in ecologically diverse species of Pseudomonas, including the opportunistic human pathogen Pseudomonas aeruginosa, the plant pathogen Pseudomonas syringae, the soil species Pseudomonas putida, and the psychrophilic Pseudomonas antarctica.

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Acknowledgements

This work was supported by a Korea Polar Research Institute (KOPRI) grant funded by the Ministry of Oceans and Fisheries (KOPRI project No. PE22900). Changhan Lee received funding from the National Research Foundation of Korea (NRF) funded by the Korean government (MSIT) (grant 2021R1C1-C1011690), the Basic Science Research Program through the NRF funded by the Ministry of Education (grant 2021R1A6-A1A10044950), and the new faculty research fund from Ajou University.

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  1. These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Biological Sciences, Ajou University, Suwon, 16499, Republic of Korea

    Hyunhee Kim, Seongjoon Moon, Soojeong Ham & Changhan Lee

  2. CJ Bioscience, Seoul, 04527, Republic of Korea

    Kihyun Lee

  3. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 171 77, Sweden

    Ute Römling

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  1. Hyunhee Kim
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Kim, H., Moon, S., Ham, S. et al. Cytoplasmic molecular chaperones in Pseudomonas species. J Microbiol. 60, 1049–1060 (2022). https://doi.org/10.1007/s12275-022-2425-0

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