Abstract
Cell-surface glycans play central roles in mediating the cell attachment and entry of many viruses, including a number of human pathogens. However, glycans are notoriously difficult to study. The emerging field of “glycovirology” aims to provide direct insight into biophysical mechanisms that determine viral tropism, to correlate glycan receptor binding with pathogenicity, and to ultimately provide a platform from which novel glycan-based antiviral strategies can be launched.
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Thilo Stehle 1983–1988 Chemiestudium an der Universität Freiburg, dort 1992 Promotion in Chemie/Strukturbiologie. 1992–1994 Postdoc an der Harvard University, Cambridge, USA. 1994–1997 Research Fellow am Howard Hughes Medical Institute, Harvard Medical School, Boston, USA. 1997–2005 Assistant Professor an der Harvard Medical School, Boston, USA. Seit 2005 Professor für Biochemie an der Universität Tübingen und Adjuct Professor of Pediatrics an der Vanderbilt University School of Medicine, Nashville, USA. (Foto: Jörg Abendroth, MPI für Entwicklungsbiologie, Tübingen)
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Stehle, T. Was ist Glykovirologie?. Biospektrum 23, 624–626 (2017). https://doi.org/10.1007/s12268-017-0845-x
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DOI: https://doi.org/10.1007/s12268-017-0845-x