Abstract
Partitioning and inheritance of mitochondria upon cell division depends on cytoskeleton-dependent transport and organelle anchoring sites at the cell cortex. In asymmetrically dividing cells the mitochondria of both daughter cells may differ in their properties. In yeast cells intact mitochondria are transported towards the bud whereas old and damaged organelles are retained in the mother cell. Similarly, in stem cell division young mitochondria are selected to maintain stem cell properties.
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Stefan Böckler Jahrgang 1986. Studium der Biologie (BSc), Biochemie und Molekularbiologie (MSc) an den Universitäten Erlangen und Bayreuth. Seit 2011 Promotion an der Universität Bayreuth
Nadine Hock Jahrgang 1986. Studium der Biologie (BSc), Biochemie und Molekularbiologie (MSc) an der Universität Bayreuth. Seit 2012 Promotion an der Universität Bayreuth.
Benedikt Westermann Jahrgang 1966. Biologiestudium (Diplom) in Hannover. 1996 Promotion bei Prof. Dr. Dr. W. Neupert an der LMU München. 1997 Postdoc bei Prof. Dr. J. E. Rothman am Sloan-Kettering Institute New York, USA. Danach Gruppenleiter an der LMU München. Seit 2003 Professor für Zellbiologie an der Universität Bayreuth.
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Böckler, S., Hock, N. & Westermann, B. Zelluläre Logistik der Mitochondrienvererbung. Biospektrum 21, 484–486 (2015). https://doi.org/10.1007/s12268-015-0604-9
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DOI: https://doi.org/10.1007/s12268-015-0604-9