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Use of Near-Infrared Autofluorescence Imaging During Thyroidectomy Associated with Improved Clinical Outcomes

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Abstract

The use of near-infrared autofluorescence imaging during thyroidectomy remains controversial. This study aimed to investigate whether the use of near-infrared autofluorescence imaging results in improved outcomes. This study was a systematic analysis using the following databases: PubMed, Cochrane Library, and Embase. Articles published prior to and during January 2021 were included. The analysis revealed that the rate of hypocalcemia after thyroidectomy in those subjected to near-infrared autofluorescence was lower than those in the control group, and this difference was statistically significant (Z = 4.82, OR = 0.41, 95% CI 0.29 ~ 0.59, P < 0.00001). The rate of inadvertent parathyroidectomy in the near-infrared autofluorescence group was lower than that in the control group, and this difference was statistically significant (Z = 2.37, OR = 0.43, 95% CI 0.22 ~ 0.86, P = 0.02). In addition, the rate of autotransplantation in the near-infrared autofluorescence group was lower than that in the control group. However, this difference was not statistically significant (Z = 1.05, OR = 0.59, 95% CI 0.22 ~ 1.57, P = 0.29). Near-infrared autofluorescence imaging was associated with significantly reduced rates of postoperative hypocalcemia and inadvertent parathyroidectomy. However, there was no statistically significant difference observed in the incidences of autotransplantation between the two groups. In conclusion, this technique results in favorable clinical outcomes and is worth popularizing. Investigate whether the use of near-infrared self-luminescence imaging can improve results. Near-infrared autoluminescence imaging significantly reduces the incidence of postoperative hypocalcemia and accidental parathyroidectomy.

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Acknowledgements

Thanks to all authors for their contributions to this article.

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Authors and Affiliations

  1. Department of Glandular Surgery, Hebei General Hospital, Shijiazhuang, 050051, Hebei, China

    Feiyue Guo, Lei Xu & Jing Zhang

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  1. Feiyue Guo
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  2. Lei Xu
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  3. Jing Zhang
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Contributions

FG was involved in the conception and design of the study. LX and FG were involved in the data collection. FG participated in the analysis and interpretation of the data. The writing of the manuscript is done by all the authors.

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Correspondence to Jing Zhang.

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Guo, F., Xu, L. & Zhang, J. Use of Near-Infrared Autofluorescence Imaging During Thyroidectomy Associated with Improved Clinical Outcomes. Indian J Surg (2022). https://doi.org/10.1007/s12262-022-03375-7

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