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Successful treatment of Hodgkin lymphoma in second trimester of pregnancy: feasibility of ABVD regimen

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Abstract

A 34-year-old woman at 18 weeks of gestation during her third pregnancy was diagnosed with Hodgkin lymphoma stage IVA. She was treated with standard ABVD and showed good response. After three-and-a-half courses of ABVD, she spontaneously delivered a healthy baby girl at 41 weeks of gestation. She continued chemotherapy after delivery. A total of six courses of ABVD were given. Complete remission was obtained and has continued for 6 months post chemotherapy. Neither mother nor child developed any infections during the observation period. The child has also shown no physiological or developmental abnormalities. Here, we describe the feasibility and safety of the ABVD regimen for the treatment of Hodgkin lymphoma, and discuss the optimal treatment strategy.

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Authors and Affiliations

  1. Department of Internal Medicine, Nihon University School of Medicine, Nerima-Hikarigaoka Hospital, 2-11-1 Hikarigaoka, Nerima-Ku, Tokyo, 179-0072, Japan

    Noriyoshi Iriyama, Akira Horikoshi, Toshitake Tanaka & Hitomi Kodaira

  2. Department of Hematology and Rheumatology, Nihon University School of Medicine, Itabashi Hospital, 30-1 Oyaguchi Kami-cho, Itabashi-Ku, Tokyo, 173-8610, Japan

    Yukio Hirabayashi, Yoshihiro Hatta & Jin Takeuchi

Authors
  1. Noriyoshi Iriyama
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  2. Akira Horikoshi
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  3. Toshitake Tanaka
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  4. Yukio Hirabayashi
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  5. Hitomi Kodaira
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  6. Yoshihiro Hatta
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  7. Jin Takeuchi
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Correspondence to Noriyoshi Iriyama.

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Iriyama, N., Horikoshi, A., Tanaka, T. et al. Successful treatment of Hodgkin lymphoma in second trimester of pregnancy: feasibility of ABVD regimen. Int J Hematol 94, 104–107 (2011). https://doi.org/10.1007/s12185-011-0876-x

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  • DOI: https://doi.org/10.1007/s12185-011-0876-x

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