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Evaluation of Nasal Mucociliary Clearance as an Indicator of Nasal Function in Obsessive-Compulsive Patients: A Cross-Sectional Study

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Abstract

This clinical study aimed to compare the mucociliary clearance time in patients with OCD, a disease associated with neural olfactory disorders, with a healthy control group. The mucociliary clearance time of fifty-one patients with OCD and fifty-two healthy patients (control group) was compared. The saccharin nasal mucociliary clearance test (NMCT) was applied and recorded the sociodemographic data of all participants. The NMCT was longer in OCD patients than healthy controls. There was no statistically significant difference in sociodemographic data between the groups. Our results show that olfactory transmission pathways may be affected in OCD patients.

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Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors declared that this study received no financial support.

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Authors and Affiliations

  1. Department of Otolaryngology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey

    Mehtap Koparal, Sevinc Hepkarsi, Mehmet Karataş & Cüneyt Yılmazer

  2. Kahta State Hospital Psychiatry Clinic, Adiyaman, Turkey

    Yasar Kapici

  3. Department of Internal Medicine, Adıyaman Training and Research Hospital, Adiyaman, Turkey

    Sefer Aslan

Authors
  1. Mehtap Koparal
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  2. Yasar Kapici
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  3. Sefer Aslan
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  4. Sevinc Hepkarsi
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  5. Mehmet Karataş
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  6. Cüneyt Yılmazer
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All co-authors have seen and agree with the contents of the manuscript and there is no financial interest to report. We certify that the submission is original work and is not under review at any other publication.

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Correspondence to Sevinc Hepkarsi.

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Compliance with Ethical Standards

The ethics committee of Adiyaman University approved the research protocol (date 24.05.2022, IRB no. 2022/5–30).

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No conflict of interest was declared by the authors.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Koparal, M., Kapici, Y., Aslan, S. et al. Evaluation of Nasal Mucociliary Clearance as an Indicator of Nasal Function in Obsessive-Compulsive Patients: A Cross-Sectional Study. Indian J Otolaryngol Head Neck Surg 75, 3263–3267 (2023). https://doi.org/10.1007/s12070-023-03972-2

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  • DOI: https://doi.org/10.1007/s12070-023-03972-2

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