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The role of various interleukins in acute myeloid leukemia

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Abstract

Interleukins are signaling molecules involved in the immune system, and they play a variety of roles in different diseases and cancers. Acute myeloid leukemia (AML) is the most common type of leukemia in adults, and survival rate after diagnosis is very low. Investigating the role interleukins play in AML can help understand the progression of the disease. There exists a need for more effective treatment of AML. Interleukins can be used to guide immunotherapy for AML. This review article will examine how specific interleukins play a role in AML disease progression and how they can be utilized as a future treatment option.

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Acknowledgements

This study was supported by the Grant of IOER 112-3749 for Yujiang Fang.

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Author notes

  1. Erin C. Kaser and Lei Zhao have contributed equally to this work.

Authors and Affiliations

  1. Department of Microbiology, Immunology and Pathology, Des Moines University College of Osteopathic Medicine, Des Moines, IA, 50312, USA

    Erin C. Kaser, Kyle P. D’mello, Huaping Xiao & Yujiang Fang

  2. The Department of Respiratory Medicine, The 2nd People’s Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei, China

    Lei Zhao

  3. Department of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, USA

    Ziwen Zhu, Mark R. Wakefield, Qian Bai & Yujiang Fang

  4. The Affiliated Hospital of Xiangnan University, Chenzhou, Hunan, China

    Huaping Xiao

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  1. Erin C. Kaser
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Correspondence to Yujiang Fang.

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Kaser, E.C., Zhao, L., D’mello, K.P. et al. The role of various interleukins in acute myeloid leukemia. Med Oncol 38, 55 (2021). https://doi.org/10.1007/s12032-021-01498-7

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