Skip to main content

Advertisement

Log in

Surgical and medical management of mesenteric ischemia

  • Published:
Current Treatment Options in Cardiovascular Medicine Aims and scope Submit manuscript

Opinion statement

Acute mesenteric ischemia frequently results in bowel necrosis, which necessitates laparotomy to assess bowel viability. Reduction in mortality requires a high index of suspicion and prompt diagnosis. Bowel resection should be preceded by visceral artery revascularization. Medical management includes the use of anticoagulation, vasodilators, and the use of inhibitors of reperfusion injury. The management of chronic mesenteric ischemia largely depends on the general condition of the patient, who is often affected by malnutrition and dehydration. Surgery, although associated with greater morbidity and mortality, is more durable and effective in relieving the symptoms of chronic mesenteric ischemia. Endovascular treatment options for chronic mesenteric ischemia include percutaneous balloon angioplasty and stenting. This treatment is more likely to be successful in dealing with stenotic rather than occlusive lesions and offers a minimal invasive approach but is associated with a smaller primary success rate and a higher recurrence rate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References and Recommended Reading

  1. Martinez JP, Hogan GJ: Mesenteric ischemia. Emerg Med Clin North Am 2004, 22:909–928. This review article provides a concise compendium, including etiology, diagnostic techniques, and therapeutic options, concerning mesenteric ischemia.

    Article  PubMed  Google Scholar 

  2. Bassiouni HS: Nonocclusive mesenteric ischemia. Surg Clin North Am 1997, 77:319–326.

    Article  Google Scholar 

  3. Heys SD, Brittenden J, Crofts TJ: Acute mesenteric ischemia: the continuing difficulty in early diagnosis. Postgrad Med J 1993, 69:48–51.

    Article  PubMed  CAS  Google Scholar 

  4. Brandt LJ, Boley SJ: AGA technical review on intestinal ischemia. American Gastrointestinal Association. Gastroenterology 2000, 118:954–968.

    Article  PubMed  CAS  Google Scholar 

  5. Moens AL, Claeys MJ, Timmermans JP, Vrints CJ: Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process. Int J Cardiol 2005, 100:179–190.

    Article  PubMed  CAS  Google Scholar 

  6. Guan W, Osanai T, Kamada T, et al.: Effect of allopurinol pretreatment on free radical generation after primary coronary angioplasty for acute myocardial infarction. J Cardiovasc Pharmacol 2003, 41:699–705.

    Article  PubMed  CAS  Google Scholar 

  7. Oldenburg WA, Lau LL, Rodenberg TJ, et al.: Acute mesenteric ischemia: a clinical review. Arch Intern Med 2004, 164:1054–1062.

    Article  PubMed  Google Scholar 

  8. Leduc FJ, Pestieau SR, Detry O, et al.: Acute mesenteric ischaemia: minimal invasive management by combined laparoscopy and percutaneous transluminal angioplasty. Eur J Surg 2000, 166:345–347.

    Article  PubMed  CAS  Google Scholar 

  9. Gallego AM, Ramirez P, Rodriguez JM, et al.: Role of urokinase in the superior mesenteric artery embolism. Surgery 1996, 120:111–113.

    Article  PubMed  CAS  Google Scholar 

  10. Brunaud L, Antunes L, Collinet-Adler S, et al.: Acute mesenteric venous thrombosis: case for nonoperative management. J Vasc Surg 2001, 34:673–679.

    Article  PubMed  CAS  Google Scholar 

  11. Rhee RY, Gloviczki P, Mendonca CT, et al.: Mesenteric venous thrombosis: still a lethal disease in the 1990s. J Vasc Surg 1994, 20:688–697.

    PubMed  CAS  Google Scholar 

  12. Kazmers A: Operative management of chronic mesenteric ischemia. Ann Vasc Surg 1998, 12:299–308. The author presents a comprehensive description of surgical techniques for splanchnic artery reconstruction, including clear, nicely drawn illustrations.

    Article  PubMed  CAS  Google Scholar 

  13. Seelig MH, Klingler PJ, Oldenburg WA: Simultaneous aortic surgery and malnutrition increase morbidity after revascularisation of the mesenteric arteries. Eur J Surg 2000, 166:721–776.

    Article  Google Scholar 

  14. Chang JB, Stein TA: Mesenteric ischemia: acute and chronic. Ann Vasc Surg 2003, 17:323–328.

    Article  PubMed  Google Scholar 

  15. Kasirajan K, O’Hara PJ, Gray BH, et al.: Chronic mesenteric ischemia: open surgery versus percutaneous angioplasty and stenting. J Vasc Surg 2001, 33:63–71.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Falkensammer, J., Oldenburg, W.A. Surgical and medical management of mesenteric ischemia. Curr Treat Options Cardio Med 8, 137–143 (2006). https://doi.org/10.1007/s11936-006-0006-x

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11936-006-0006-x

Keywords

Navigation