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Recent Advances in Myotonic Dystrophy Type 2

  • Nerve and Muscle (L Weimer, Section Editor)
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Abstract

Myotonic dystrophy is the commonest adult muscular dystrophy. Myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2) are often discussed jointly, and although they share many clinical and molecular features, differences do exist. Historically, more is known about DM1 than about DM2. The literature in the field of myotonic dystrophy is broad, with advances in our understanding of DM2. This article reviews recent developments in DM2 with respect to diagnosis, systemic features, and molecular mechanisms of the disease.

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Acknowledgments

We thank Lewis P. Rowland for inspiration, wisdom, and guidance.

Compliance with Ethics Guidelines

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Conflict of Interest

Christina M. Ulane and Sarah Teed declare that they have no conflict of interest.

Jacinda Sampson has received a grant from the Marigold Foundation for myotonic dystrophy support group development. She also has received honorarium and paid travel expenses from the Myotonic Dystrophy Foundation for her role as a guest speaker.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Neurology, The Neurological Institute, Columbia University Medical Center, 710 West 168 St., New York, NY, 10032, USA

    Christina M. Ulane

  2. Gertrude H. Sergievsky Center, Columbia University Medical Center, 710 West 168 St., New York, NY, 10032, USA

    Sarah Teed

  3. Gertrude H. Sergievsky Center, Department of Neurology, The Neurological Institute, Columbia University Medical Center, 710 West 168 St., New York, NY, 10032, USA

    Jacinda Sampson

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  1. Christina M. Ulane
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  2. Sarah Teed
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Correspondence to Jacinda Sampson.

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This article is part of the Topical Collection on Nerve and Muscle

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Ulane, C.M., Teed, S. & Sampson, J. Recent Advances in Myotonic Dystrophy Type 2. Curr Neurol Neurosci Rep 14, 429 (2014). https://doi.org/10.1007/s11910-013-0429-1

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