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Contrast-enhanced ultrasound of the kidney: a single-institution experience

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Abstract

Background

Focal renal masses are typically evaluated by means of triphasic contrast-enhanced CT or MRI scan but use of iodinated contrast or gadolinium is unsuitable for some patients. Contrast-enhanced ultrasound (CEUS) is an imaging alternative in this scenario but has limited availability in Ireland.

Aim

The aim of the study was to retrospectively evaluate experience with selective use of CEUS for non-invasive characterization of focal renal masses in a tertiary referral institution in Ireland, with a particular focus on cystic renal lesions and the influence of CEUS on final Bosniak classification and treatment outcomes.

Methods

All cases of renal CEUS between 2009 and 2017 were identified. Imaging history, patient records, histopathology reports, urology conference notes, clinical follow-up details, details of lesion progression or stability on surveillance, biopsy and/or resection details and pre- and post-CEUS Bosniak scores were recorded.

Results

Thirty-one patients underwent renal CEUS (7 solid renal lesions, 21 cystic renal lesions and 3 ‘indeterminate’ renal lesions). After CEUS, the CEUS-modified Bosniak score was upgraded in nine patients and downgraded in two patients. All three lesions upgraded from Bosniak III to IV were renal cell carcinomas. One of two lesions downgraded from Bosniak IV to III was resected (cystic nephroma) and the other showed no progression after 19 months of surveillance.

Conclusion

CEUS is a valuable alternative to CT in assessing complex cystic or solid renal lesions where iodinated CT contrast or gadolinium is inappropriate. CEUS can also refine the Bosniak category of atypical cystic renal lesions and help facilitate treatment decisions.

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Authors and Affiliations

  1. Department of Radiology, St. Vincent’s University Hospital, Dublin, Ireland

    Sheng F. Oon, Robert W. Foley, Deirdre Quinn & Robert G. Gibney

  2. Department of Urology, St. Vincent’s University Hospital, Dublin, Ireland

    David M. Quinlan

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  1. Sheng F. Oon
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  2. Robert W. Foley
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Correspondence to Sheng F. Oon.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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The authors declare that they have no conflict of interest.

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Oon, S.F., Foley, R.W., Quinn, D. et al. Contrast-enhanced ultrasound of the kidney: a single-institution experience. Ir J Med Sci 187, 795–802 (2018). https://doi.org/10.1007/s11845-017-1725-6

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  • DOI: https://doi.org/10.1007/s11845-017-1725-6

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