Skip to main content

Advertisement

SpringerLink
Log in

Current Researches in Modular Biofabrication: Tissue Building Blocks and Bioreactors

  • Review Article
  • Published:
Korean Journal of Chemical Engineering Aims and scope Submit manuscript

Abstract

Modular tissue engineering (TE) is based on the design, fabrication, and arrangement of replicated microtissue constructs to generate functional tissues. The advantage of this strategy is to produce tissues that more closely mimic the complex structure of native tissues/organs. High-precision technologies such as microfluidics, 3D bioprinting, and electrospinning, which support both cell- and scaffold-based biofabrication methods, are implemented in a bottom-up TE strategy. Bioreactors are used in the last step of the tissue production process. Packed bed perfusion bioreactors are widely applied in bottom-up tissue engineering due to their ability to control perfusion to tissues. Modeling and simulation software packages are used as powerful tools to predict the perfusion and flow distribution to the tissues and to design robust bioreactors. This review imparts on the recent advances in the field of bottom-up TE process and provides comprehensive insights into the cell-based and scaffold-based strategies used for the biofabrication/assembly of tissue building blocks (BBs). Microfluidic devices and 3D-bioprinting technology are mentioned as precise controlling tools in this regard, the promoted applications of which are swiftly growing.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

(Reproduced with permission from [120])

Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

Abbreviations

TE:

Tissue engineering

BBs:

Building blocks

ECM:

Extracellular matrix

hAD-MSCs:

Human adipose-derived mesenchymal stem cells

hAD-SCs:

Human adipose-derived stromal cells

UVECs:

Umbilical vein endothelial cells

AF:

Annulus fibrosus

ChP:

Choroid plexus

hPSC:

Human pluripotent stem cell

PLLA:

Poly L-lactic acid

PCL:

Polycaprolactone

MNCs:

Magnetic nanoparticle clusters

GI:

Gastrointestinal

dECM:

Decellularized ECM

PLGA:

Poly D, L-lactic-co-glycolic acid

HPGs:

Hollow pollen grains

CFD:

Computational fluid dynamics

dccECM:

Decellularized calf cardiac ECM

CNTs:

Carbon nanotubes

AAB:

Aspiration-assisted bioprinting

GMMH:

Gelatin methacryloyl methacrylated hyaluronic acid

CNCs:

Cellulose nanocrystals

References

  1. S. Abadpour, E.M. Niemi, L. Strid Orrhult, L.P. Nogueira, H.J. Haugen, D. Josefsen, G. Kvalheim, S. Krauss, P. Gatenholm, H. Scholz, Transplantation 105, S25 (2021)

    Article  Google Scholar 

  2. A. R. Abdel Fattah, N. Kolaitis, K. Van Daele, G. Rustandi and A. Ranga, BioRxiv, 2022.03. 17.484696 (2022)

  3. A. Abrishamkar, A. Nilghaz, M. Saadatmand, M. Naeimirad, A.J. DeMello, Biomicrofluidics 16, 061504 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. T. Ahmad, H. Byun, J. Lee, S.K.M. Perikamana, Y.M. Shin, E.M. Kim, H. Shin, Biomaterials 230, 119652 (2020)

    Article  CAS  PubMed  Google Scholar 

  5. M. Akbari, A. Tamayol, S. Bagherifard, L. Serex, P. Mostafalu, N. Faramarzi, M.H. Mohammadi, A. Khademhosseini, Adv. Healthcare Mater. 5, 751 (2016)

    Article  CAS  Google Scholar 

  6. G. Al-Kharusi, N.J. Dunne, S. Little, T.J. Levingstone, Bioengineering 9, 561 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. A. Alghuwainem, A.T. Alshareeda, B. Alsowayan, Int. J. Mol. Sci. 20, 4926 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. A.R. Ameri, A. Imanparast, M. Passandideh-Fard, S.A.M. Shaegh, Anal. Chim. Acta 1221, 340093 (2022)

    Article  CAS  PubMed  Google Scholar 

  9. C. An, R. Zhou, H. Zhang, Y. Zhang, W. Liu, J. Liu, B. Bao, K. Sun, C. Ren, Y. Zhang, Acta Biomater.Biomater. 157, 91 (2023)

    Article  CAS  Google Scholar 

  10. J.P. Armstrong, M.M. Stevens, Trends Biotechnol.Biotechnol. 38, 254 (2020)

    Article  CAS  Google Scholar 

  11. B. Ayan, D.N. Heo, Z. Zhang, M. Dey, A. Povilianskas, C. Drapaca, I.T. Ozbolat, Sci. Adv. 6, eaaw5111 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. K. Banerjee, J. Radhakrishnan, N. Ayyadurai, P. Ganesan, N.R. Kamini, J. Sci. Adv. Mater. Devices 7, 100491 (2022)

    Article  CAS  Google Scholar 

  13. G. Basara, S.G. Ozcebe, B.W. Ellis, P. Zorlutuna, Gels 7, 70 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. C.C. Beauchesne, M. Chabanon, B. Smaniotto, B. Ladoux, B. Goyeau, B. David, Tissue Eng. Regen. Med. 17, 301 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. M. Borries, Y.F. Barooji, S. Yennek, A. Grapin-Botton, K. Berg-Sørensen, L.B. Oddershede, Front. Phys. 8, 579168 (2020)

    Article  Google Scholar 

  16. J.A. Brassard, M. Nikolaev, T. Hübscher, M. Hofer, M.P. Lutolf, Nat. Mater. 20, 22 (2021)

    Article  CAS  PubMed  Google Scholar 

  17. M. Brunelli, C. Perrault, D. Lacroix, Multiscale Mechanobiol. Tissue Eng. 3, 1 (2019)

    Google Scholar 

  18. E. Capuana, F.C. Pavia, M.E. Lombardo, S. Rigogliuso, G. Ghersi, V. La Carrubba, V. Brucato, Biochem. Eng. J.. Eng. J. 178, 108298 (2022)

    Article  CAS  Google Scholar 

  19. F. Carotenuto, N. Fiaschini, P. Di Nardo, A. Rinaldi, Materials 16, 1539 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. J.M. Chemmarappally, H.C. Pegram, N. Abeywickrama, E. Fornari, A.J. Hargreaves, L.A. De Girolamo, B. Stevens, Sci. Rep. 10, 1 (2020)

    Article  Google Scholar 

  21. A.M. Chen, M. Lashmet, A. Isidan, J.L. Sterner, J. Walsh, C. Koehler, P. Li, B. Ekser, L. Smith, Sci. Rep. 10, 7237 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Y.-S. Chen, L.-Y. Ke, S.-Y. Wei, M.S. Poddar, C.-H. Liu, Sens. Actuators B Chem. 352, 131048 (2022)

    Article  CAS  Google Scholar 

  23. Y.J. Chuah, J.R. Tan, Y. Wu, C.S. Lim, H.T. Hee, Y. Kang, D.-A. Wang, Acta Biomater.Biomater. 107, 129 (2020)

    Article  CAS  Google Scholar 

  24. C. Czichy, D. Kilian, T.-C. Wang, S. Günther, A. Lode, M. Gelinsky, S. Odenbach, J. Mech. Behav. Biomed. Mater.Behav. Biomed. Mater. 131, 105253 (2022)

    Article  CAS  Google Scholar 

  25. A.C. Daly, M.D. Davidson, J.A. Burdick, Nat. Commun. 12, 753 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. J.P. de Lucena-Thomas, P. Boonprasirt, K. Luetchford, P. De Bank, M. Ellis, Biochem. Eng. J. 160, 107632 (2020)

    Article  CAS  Google Scholar 

  27. A. De Pieri, Y. Rochev, D.I. Zeugolis, npj Regen. Med. 6, 18 (2021)

    Google Scholar 

  28. D. Egger, S. Nebel, M. Gensler, S. Kreß, J. Hansmann, C. Kasper, Tissue Engineering (Elsevier, 2023), pp.431–456

    Book  Google Scholar 

  29. B. Elveren, M. Kurečič, T. Maver, U. Maver, Adv. Biol. 7, 2300057 (2023)

    Article  CAS  Google Scholar 

  30. A. Engberg, C. Stelzl, O. Eriksson, P. O’Callaghan, J. Kreuger, Sci. Rep. 11, 21547 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. A. Fallahi, A. Khademhosseini, A. Tamayol, Trends Biotechnol.Biotechnol. 34, 683 (2016)

    Article  CAS  Google Scholar 

  32. T. Feijão, M.I. Neves, A. Sousa, A.L. Torres, S.J. Bidarra, I.D. Orge, D.T.O. Carvalho, C.C. Barrias, Biomaterials 279, 121222 (2021)

    Article  PubMed  Google Scholar 

  33. R. Fekrazad, F. Tondnevis, M.M. Abolhasani, J. Biomed. Phys. Eng. 12, 395 (2022)

    Article  PubMed  PubMed Central  Google Scholar 

  34. Q. Gao, P. Zhao, R. Zhou, P. Wang, J. Fu, Y. He, Bio-Des. Manuf. 2, 1 (2019)

    Article  Google Scholar 

  35. V. Goranov, T. Shelyakova, R. De Santis, Y. Haranava, A. Makhaniok, A. Gloria, A. Tampieri, A. Russo, E. Kon, M. Marcacci, Sci. Rep. 10, 1 (2020)

    Article  Google Scholar 

  36. K.H. Griffin, S.W. Fok, J. Kent Leach, npj Regener. Med. 7, 70 (2022)

    Article  Google Scholar 

  37. S.P. Grogan, E.W. Dorthé, N.E. Glembotski, F. Gaul, D.D. D’Lima, Connect. Tissue Res. 61, 229 (2020)

    Article  CAS  PubMed  Google Scholar 

  38. O. Guillaume, O. Kopinski-Grünwald, G. Weisgrab, T. Baumgartner, A. Arslan, K. Whitmore, S. Van Vlierberghe, A. Ovsianikov, Acta Biomater. 165, 72 (2023)

    Article  CAS  PubMed  Google Scholar 

  39. J. He, Y. Pang, H. Yang, K. Montagne, M. Shinohara, Y. Mao, W. Sun, Y. Sakai, Ann. Transl. Med. 8, 1400 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  40. R. Hegab, T. Van Volkenburg, K. Ohiri, N. Sebeck, S. Bessling, M. Theodore, K. Rossick, M. Pellicore, J. Benkoski, J. Patrone, Biomed. Phys. Eng. Express 8, 035012 (2022)

    Article  Google Scholar 

  41. D.N. Heo, B. Ayan, M. Dey, D. Banerjee, H. Wee, G.S. Lewis, I.T. Ozbolat, Biofabrication 13, 015013 (2020)

    Article  Google Scholar 

  42. S. Heydarkhan-Hagvall, K. Schenke-Layland, A.P. Dhanasopon, F. Rofail, H. Smith, B.M. Wu, R. Shemin, R.E. Beygui, W.R. MacLellan, Biomaterials 29, 2907 (2008)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  43. C. Hoefner, C. Muhr, H. Horder, M. Wiesner, K. Wittmann, D. Lukaszyk, K. Radeloff, M. Winnefeld, M. Becker, T. Blunk, Tissue Eng. Part A 26, 915 (2020)

    Article  CAS  PubMed  Google Scholar 

  44. M. Hofer, M.P. Lutolf, Nat. Rev. Mater. 6, 402 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. J. Hong, M. Yeo, G.H. Yang, G. Kim, Int. J. Mol. Sci. 20, 6208 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. T.-Y. Huang, H.-W. Huang, D. Jin, Q. Chen, J. Huang, L. Zhang, H. Duan, Sci. Adv. 6, eaav8219 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  47. S.N. Jayasinghe, Matter 5, 4 (2022)

    Article  CAS  Google Scholar 

  48. N.N. Kachouie, Y. Du, H. Bae, M. Khabiry, A.F. Ahari, B. Zamanian, J. Fukuda, A. Khademhosseini, Organogenesis 6, 234 (2010)

    Article  PubMed  PubMed Central  Google Scholar 

  49. R. Karuppal, J. Orthop.Orthop. 14, A1 (2017)

    Article  Google Scholar 

  50. Y. Kasai, R. Takagi, S. Kobayashi, T. Owaki, N. Yamaguchi, H. Fukuda, Y. Sakai, Y. Sumita, N. Kanai, H. Isomoto, Regener. Ther. 14, 87 (2020)

    Article  Google Scholar 

  51. S. Kim, Y.S. Choi, J.S. Lee, S.-H. Jo, Y.-G. Kim, S.-W. Cho, J. Ind. Eng. Chem. 107, 155 (2022)

    Article  CAS  Google Scholar 

  52. S. Kim, S. Min, Y.S. Choi, S.-H. Jo, J.H. Jung, K. Han, J. Kim, S. An, Y.W. Ji, Y.-G. Kim, Nat. Commun.Commun. 13, 1692 (2022)

    Article  CAS  Google Scholar 

  53. Y. Kim, Y.W. Kim, S.B. Lee, K. Kang, S. Yoon, D. Choi, S.-H. Park, J. Jeong, Biomaterials 274, 120899 (2021)

    Article  CAS  PubMed  Google Scholar 

  54. G.S. Kronemberger, G.M. Dalmônico, A.L. Rossi, P.E.C. Leite, A.M. Saraiva, A. Beatrici, K.R. Silva, J.M. Granjeiro, L.S. Baptista, Artif. Organs 44, E288 (2020)

    Article  CAS  PubMed  Google Scholar 

  55. G.S. Kronemberger, R.A.M. Matsui, Gd.A.S. de Castro, World J. Stem Cells 12, 110 (2020)

    Article  PubMed  PubMed Central  Google Scholar 

  56. S. Laboy-López, P.O. Méndez Fernández, J.G. Padilla-Zayas, E. Nicolau, Int. J. Biomater. 2022, 3255039 (2022)

    Article  PubMed  PubMed Central  Google Scholar 

  57. H. Lee, J.S. Im, D.B. Choi, J. An, S.-B. Kim, S. Yeon, S. Yoon, D.-H. Woo, Organoid 2, e14 (2022)

    Article  Google Scholar 

  58. J.S.-J. Lee, S.-J. Kim, J.S. Choi, M.R. Eom, H. Shin, S.K. Kwon, J. Ind. Eng. Chem. 91, 296 (2020)

    Article  CAS  Google Scholar 

  59. A. Leferink, M. Tibbe, E. Bossink, L. de Heus, H. van Vossen, A. van den Berg, L. Moroni, R. Truckenmüller, Mater. Today Bio 4, 100025 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  60. A. Levin, V. Sharma, L. Hook, E. García-Gareta, J. Tissue Eng. 9, 2041731418781696 (2018)

    Article  PubMed  PubMed Central  Google Scholar 

  61. S. Li, Y. Hang, Z. Ding, Q. Lu, G. Lu, H. Chen, D.L. Kaplan, ACS Biomater. Sci. Eng.Biomater. Sci. Eng. 6, 2847 (2020)

    Article  CAS  Google Scholar 

  62. X. Li, B. You, H.C. Shum, C.-H. Chen, Biomaterials 287, 121631 (2022)

    Article  CAS  PubMed  Google Scholar 

  63. Y. Li, G. Huang, X. Zhang, L. Wang, Y. Du, T.J. Lu, F. Xu, Biotechnol. Adv.. Adv. 32, 347 (2014)

    Article  CAS  Google Scholar 

  64. H. Liu, Y. Du, J.-P. St-Pierre, M.S. Bergholt, H. Autefage, J. Wang, M. Cai, G. Yang, M.M. Stevens, S. Zhang, Sci. Adv. 6, eaay7608 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  65. X. Liu, L. Li, B. Gaihre, S. Park, Y. Li, A. Terzic, B. D. Elder and L. Lu 16, 2741 (2022)

    CAS  Google Scholar 

  66. Y. Liu, Z. Chen, J. Xu, Green. Chem. Eng. 5, 16 (2023)

    Google Scholar 

  67. Y. Liu, R. Wang, S. Ding, L. Deng, Y. Zhang, J. Li, Z. Shi, Z. Wu, K. Liang, X. Yan, Biomaterials 287, 121615 (2022)

    Article  CAS  PubMed  Google Scholar 

  68. S. Lopa, F. Piraino, G. Talò, V.L. Mainardi, S. Bersini, M. Pierro, L. Zagra, M. Rasponi, M. Moretti, Front. Bioeng. Biotechnol. 8, 366 (2020)

    Article  PubMed  PubMed Central  Google Scholar 

  69. T. Lu, Y. Li, T. Chen, Int. J. Nanomed.Nanomed. 8, 337 (2013)

    Article  Google Scholar 

  70. K.A. Luetchford, J.B. Chaudhuri, A. Paul, Mater. Sci. Eng. C 106, 110116 (2020)

    Article  CAS  Google Scholar 

  71. M.P. Lun, E.S. Monuki, M.K. Lehtinen, Nat. Rev. Neurosci.Neurosci. 16, 445 (2015)

    Article  CAS  Google Scholar 

  72. E.A. Makris, A.H. Gomoll, K.N. Malizos, J.C. Hu, K.A. Athanasiou, Nat. Rev. Rheumatol.Rheumatol. 11, 21 (2015)

    Article  CAS  Google Scholar 

  73. J.-M.F. Martins, C. Fischer, A. Urzi, R. Vidal, S. Kunz, P.-L. Ruffault, L. Kabuss, I. Hube, E. Gazzerro, C. Birchmeier, Cell Stem Cell 26, 172 (2020)

    Article  Google Scholar 

  74. S. Mashayekhiyan, M. Jahanshahi, M. Jafarkhani, K. Entezari, M. Niazi, H. Kabir, Iran. J. Chem. Eng. (IJChE) 18, 3 (2021)

    Google Scholar 

  75. Y.T. Matsunaga, Y. Morimoto, S. Takeuchi, Adv. Mater. 23, H90 (2011)

    Article  CAS  PubMed  Google Scholar 

  76. P. Maturavongsadit, L.K. Narayanan, P. Chansoria, R. Shirwaiker, S.R. Benhabbour, ACS Appl. Bio Mater. 4, 2342 (2021)

    Article  CAS  PubMed  Google Scholar 

  77. A.P. McGuigan, M.V. Sefton, Proc. Natl. Acad. Sci. U. S. A. 103, 11461 (2006)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  78. J. Meneses, J.C. Silva, S.R. Fernandes, A. Datta, F. Castelo Ferreira, C. Moura, S. Amado, N. Alves, P. Pascoal-Faria, Polymers (Basel) 12, 940 (2020)

    CAS  PubMed  Google Scholar 

  79. M. Mueller, S. Rasoulinejad, S. Garg, S.V. Wegner, Nano Lett. 20, 2257 (2019)

    Article  PubMed  PubMed Central  Google Scholar 

  80. B. Nazari, M. Kazemi, A. Kamyab, B. Nazari, S. Ebrahimi-Barough, M. Hadjighassem, A. Norouzi-Javidan, A. Ai, A. Ahmadi, J. Ai, J. Biomed. Mater. Res. Part B Appl. Biomater. 108, 192 (2020)

    Article  CAS  Google Scholar 

  81. J.W. Nichol, A. Khademhosseini, Soft Matter 5, 1312 (2009)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  82. M. Nie, S. Takeuchi, Biofabrication 10, 044103 (2018)

    Article  PubMed  Google Scholar 

  83. A. Nishimura, R. Nakajima, R. Takagi, G. Zhou, D. Suzuki, M. Kiyama, T. Nozaki, T. Owaki, T. Takahara, S. Nagai, T. Nakamura, M. Sugaya, K. Terada, Y. Igarashi, H. Hanzawa, T. Okano, T. Shimizu and M. Yamato 13, 2246 (2019)

    CAS  Google Scholar 

  84. L. Ouyang, J.P. Armstrong, Q. Chen, Y. Lin, M.M. Stevens, Adv. Funct. Mater.Funct. Mater. 30, 1908349 (2020)

    Article  CAS  Google Scholar 

  85. L. Ouyang, J.P. Armstrong, M. Salmeron-Sanchez, M.M. Stevens, Adv. Funct. Mater.Funct. Mater. 30, 1909009 (2020)

    Article  CAS  Google Scholar 

  86. I.T. Ozbolat, J. Nanotechnol. Eng. Med. 6, 024701 (2015)

    Article  Google Scholar 

  87. Y. Pang, S. Sutoko, Z. Wang, Y. Horimoto, K. Montagne, I. Horiguchi, M. Shinohara, M. Danoy, T. Niino, Y. Sakai, Med. Eng. Phys. 76, 69 (2020)

    Article  PubMed  Google Scholar 

  88. A. Pantazis, G. Papadakis, K. Parasyris, A. Stavrinidis, E. Gizeli, Sens. Actuators B Chem. 319, 128161 (2020)

    Article  CAS  Google Scholar 

  89. D. Pearce, S. Fischer, F. Huda, A. Vahdati, Tissue Eng. Regen Med. 17, 1 (2020)

    Article  CAS  PubMed  Google Scholar 

  90. M. Peck, N. Dusserre, T.N. McAllister, N. L’Heureux, Mater. Today 14, 218 (2011)

    Article  CAS  Google Scholar 

  91. N. Pien, H. Krzyslak, S.S. Kallaje, J. Van Meerssche, D. Mantovani, C. De Schauwer, P. Dubruel, S. Van Vlierberghe, C. Pennisi, Appl. Mater. Today 31, 101737 (2023)

    Article  Google Scholar 

  92. M. Rahimnejad, N. Nasrollahi Boroujeni, S. Jahangiri, N. Rabiee, M. Rabiee, P. Makvandi, O. Akhavan, R.S. Varma, Nano-Micro Lett. 13, 182 (2021)

    Article  CAS  Google Scholar 

  93. H. Renner, M. Grabos, K.J. Becker, T.E. Kagermeier, J. Wu, M. Otto, S. Peischard, D. Zeuschner, Y. TsyTsyura, P. Disse, Elife 9, e52904 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  94. V. Rezania, D. Coombe, J. Tuszynski, J. Funct. Biomater. 11, 13 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  95. F.J.C. Rivera, J. Chen, Future Foods 6, 100195 (2022)

    Article  Google Scholar 

  96. K.O. Rojek, M. Cwiklinska, J. Kuczak, J. Guzowski, Chem. Rev. 122, 16839 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  97. A. Salerno, G. Cesarelli, P. Pedram, P.A. Netti, J. Clin. Med. 8, 1816 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  98. L.F. Santos, A.S. Silva, J.F. Mano, Acta Biomater.Biomater. 118, 18 (2020)

    Article  CAS  Google Scholar 

  99. B.S. Schon, G.J. Hooper, T.B. Woodfield, Ann. Biomed. Eng. 45, 100 (2017)

    Article  CAS  PubMed  Google Scholar 

  100. T. Sego, M. Prideaux, J. Sterner, B.P. McCarthy, P. Li, L.F. Bonewald, B. Ekser, A. Tovar, L. Jeshua Smith, Biotechnol. Bioeng.. Bioeng. 117, 798 (2020)

    Article  CAS  Google Scholar 

  101. C. Selden, B. Fuller, Bioengineering 5, 32 (2018)

    Article  PubMed  PubMed Central  Google Scholar 

  102. M. Serzanti, M. Baù, M. Demori, S. Calamaio, M. Cominelli, P.L. Poliani, P. Dell’Era, M. Ferrari, V. Ferrari, Appl. Sci. 10, 3477 (2020)

    Article  CAS  Google Scholar 

  103. R. Seyedmahmoud, P. Mozetic, A. Rainer, S.M. Giannitelli, F. Basoli, M. Trombetta, E. Traversa, S. Licoccia, A. Rinaldi, J. Biomed. Mater. Res. Part A 103, 103 (2015)

    Article  Google Scholar 

  104. R. Seyedmahmoud, A. Rainer, P. Mozetic, S. Maria Giannitelli, M. Trombetta, E. Traversa, S. Licoccia, A. Rinaldi, J. Biomed. Mater. Res. Part A 103, 91 (2015)

    Article  Google Scholar 

  105. M. R. Shaker, J. Cooper-White and E. J. Wolvetang, BioRxiv (2020)

  106. C. Simitzi, M. Vlahovic, A. Georgiou, Z. Keskin-Erdogan, J. Miller, R.M. Day, Front. Bioeng. Biotechnol. 8, 816 (2020)

    Google Scholar 

  107. M.A. Skylar-Scott, J.Y. Huang, A. Lu, A.H. Ng, T. Duenki, S. Liu, L.L. Nam, S. Damaraju, G.M. Church, J.A. Lewis, Nat. Biomed. Eng. 6, 449 (2022)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  108. M.A. Skylar-Scott, S.G.M. Uzel, L.L. Nam, J.H. Ahrens, R.L. Truby, S. Damaraju, J.A. Lewis, Sci. Adv. 5, eaaw2459 (2019)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  109. L.J. Smith, P. Li, M.R. Holland, B. Ekser, Sci. Rep. 8, 7561 (2018)

    Article  PubMed  PubMed Central  Google Scholar 

  110. H. Suhaimi, J. P. Ward and D. B. Das, Asia‐Pac. J. Chem. Eng., e2565 (2020)

  111. M. Sun, J. Gong, W. Cui, C. Li, M. Yu, H. Ye, Z. Cui, J. Chen, Y. He, A. Liu, Smart Mater. Med. 4, 111 (2022)

    Article  Google Scholar 

  112. W. Swieszkowski, M.R. Dokmeci, A. Khademhosseini, Biofabrication 12, 030201 (2020)

    Article  PubMed  Google Scholar 

  113. R. Tiruvannamalai-Annamalai, D.R. Armant, H.W. Matthew, PLoS ONE 9, e84287 (2014)

    Article  PubMed  PubMed Central  Google Scholar 

  114. A. Townsend-Nicholson, S.N. Jayasinghe, Biomacromol 7, 3364 (2006)

    Article  CAS  Google Scholar 

  115. F. Urciuolo, G. Imparato, A. Totaro, P.A. Netti, Methodist Debakey Cardiovasc. J.Debakey Cardiovasc. J. 9, 213 (2013)

    Article  Google Scholar 

  116. S. Verma, V. Khanna, S. Kumar and S. Kumar, ACS Omega (2023)

  117. J.R. Vetsch, R. Müller, S. Hofmann, J. Tissue Eng. Regen. Med. 9, 903 (2015)

    Article  CAS  PubMed  Google Scholar 

  118. X. Wang, Z. Wang, W. Zhai, F. Wang, Z. Ge, H. Yu, W. Yang, Micromachines 13, 75 (2021)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  119. X. Wang, C. Yang, Y. Yu and Y. Zhao, Research (2022)

  120. Y. Wang, H. Liu, M. Zhang, H. Wang, W. Chen, J. Qin, Biomater. Sci. 8, 5476 (2020)

    Article  CAS  PubMed  Google Scholar 

  121. W. Wei, H. Dai, Bioactive Mater. 6, 4830 (2021)

    Article  CAS  Google Scholar 

  122. Y. Wu, B. Ayan, K.K. Moncal, Y. Kang, A. Dhawan, S.V. Koduru, D.J. Ravnic, F. Kamal, I.T. Ozbolat, Adv. Healthc. Mater. 9, 2001657 (2020)

    Article  CAS  Google Scholar 

  123. Z. Wu, M. Pan, J. Wang, B. Wen, L. Lu, H. Ren, Eng. Regener. 3, 397 (2022)

    Google Scholar 

  124. C. Xie, R. Liang, J. Ye, Z. Peng, H. Sun, Q. Zhu, X. Shen, Y. Hong, H. Wu, W. Sun, X. Yao, J. Li, S. Zhang, X. Zhang, H. Ouyang, Biomaterials 288, 121741 (2022)

    Article  CAS  PubMed  Google Scholar 

  125. Y. Xie, L. Dai, Y. Yang, Biosens. Bioelectron. X 10, 100109 (2022)

    CAS  PubMed  PubMed Central  Google Scholar 

  126. G. Xu, Z. Ding, Q. Lu, X. Zhang, X. Zhou, L. Xiao, G. Lu and D. L. Kaplan, Protein Cell, 1 (2020)

  127. C. Yang, L. Kong, Z. Zhang, Nano Today 44, 101481 (2022)

    Article  CAS  Google Scholar 

  128. G. Yang, B. Mahadik, T. Mollot, J. Pinsky, A. Jones, A. Robinson, D. Najafali, D. Rivkin, J. Katsnelson, C. Piard, J.P. Fisher, Tissue Eng. Part A 26, 1369 (2020)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  129. P. Yang, Y. Ju, Y. Hu, X. Xie, B. Fang, L. Lei, Biomater. Res. 27, 1 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  130. M. Yeo, G. Kim, Chem. Eng. J. 275, 27 (2015)

    Article  CAS  Google Scholar 

  131. J. Zhang, E. Wehrle, P. Adamek, G.R. Paul, X.H. Qin, M. Rubert, R. Müller, Acta Biomater.Biomater. 114, 307 (2020)

    Article  CAS  Google Scholar 

  132. Y.S. Zhang, A. Arneri, S. Bersini, S.-R. Shin, K. Zhu, Z. Goli-Malekabadi, J. Aleman, C. Colosi, F. Busignani, V. Dell’Erba, Biomaterials 110, 45 (2016)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  133. Y. S. Zhang, Q. Pi and A. M. van Genderen, J. Vis. Exp. JoVE (2017)

  134. J. Zhao, M. Griffin, J. Cai, S. Li, P.E. Bulter, D.M. Kalaskar, Biochem. Eng. J. 109, 268 (2016)

    Article  CAS  Google Scholar 

  135. L. Zhao, X. Wang, TrAC Trends Analyt. Chem. 158, 116864 (2022)

    Article  Google Scholar 

  136. Y. Zhao, E.Y. Wang, F.B. Lai, K. Cheung, M. Radisic, Trends Biotechnol. 41, 410 (2023)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  137. Z. Zhao, X. Chen, A.M. Dowbaj, A. Sljukic, K. Bratlie, L. Lin, E.L.S. Fong, G.M. Balachander, Z. Chen, A. Soragni, M. Huch, Y.A. Zeng, Q. Wang, H. Yu, Nat. Rev. Methods Prim. 2, 94 (2022)

    Article  CAS  Google Scholar 

  138. L. Zwi-Dantsis, B. Wang, C. Marijon, S. Zonetti, A. Ferrini, L. Massi, D.J. Stuckey, C.M. Terracciano, M.M. Stevens, Adv. Mater. 32, 1904598 (2020)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This review is part of a Ph.D. thesis supported by the Drug Applied Research Center (# 58781) and conducted at the Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences.

Author information

Author notes

  1. Solmaz Zakhireh and Ali Mesgari-Shadi authors contributed equally to this work.

Authors and Affiliations

  1. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

    Solmaz Zakhireh & Khosro Adibkia

  2. Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran

    Solmaz Zakhireh, Ali Mesgari-Shadi & Khosro Adibkia

  3. Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, Fort Lauderdale, FL, 33328, USA

    Jaleh Barar & Yadollah Omidi

  4. Chemical Engineering Department, Faculty of Engineering, Azarbaijan Shahid Madani University, Tabriz, Iran

    Younes Beygi-Khosrowshahi

  5. Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran

    Khosro Adibkia

Authors
  1. Solmaz Zakhireh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ali Mesgari-Shadi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jaleh Barar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yadollah Omidi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Younes Beygi-Khosrowshahi
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Khosro Adibkia
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Khosro Adibkia.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zakhireh, S., Mesgari-Shadi, A., Barar, J. et al. Current Researches in Modular Biofabrication: Tissue Building Blocks and Bioreactors. Korean J. Chem. Eng. (2024). https://doi.org/10.1007/s11814-024-00059-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11814-024-00059-8

Keywords

Search

Navigation