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The measurement of the left ventricle ejection fraction by a bedside FoCUS examination

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Abstract

The use of point-of-care ultrasound is rapidly increasing in medical practice. This study aims to evaluate the left ventricle systolic function by the bedside focus cardiac ultrasound (FoCUS). We consecutively enrolled n.59 patients of the Emergency Medicine Unit of S. Andrea Hospital. Every patient received a bedside FoCUS examination to estimate the left ventricle (LV) ejection fraction (EF); the LV EF measurements were compared with those obtained by standard echocardiography (as gold standard). The LV EF obtained by the bedside FoCUS examination and the standard echocardiography, resulted, respectively: 50.2 ± 15.1% (by the Quinones equation), 39.5 + 12.0% (by the Lvivo app) and 53.7 + 11.1% (by the standard echocardiography). The correlations between the bedside FoCUS EF measurements versus standard echocardiography were statistically significant: r =  + 0.694 p < 1.9 × 10–6 (Quinones equation, Bland–Altman analysis mean = − 2.3%) and r =  + 0.571 p < 0.01 (Lvivo app, Bland–Altman analysis mean = − 13.3%). In conclusion, the present study showed a high accuracy of the bedside FoCUS EF evaluations, which may support the diagnosis of the heart failure in an emergency setting without delaying. The EF measurements by the operational method are more precise than those obtained by the unselected images of the software application.

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References

  1. Díaz-Gómez JL, Mayo PH, Koenig SJ (2021) Point-of-care ultrasonography. N Engl J Med 385:1593–1602

    Article  PubMed  Google Scholar 

  2. Neskovic AN, Edvardsen T, Galderisi M, Garbi M, Gullace G, Jurcut R, Dalen H, Hagendorff A, Lancellotti P, European Association of Cardiovascular Imaging Document Reviewers, Popescu BA, Sicari R, Stefanidis A (2014) Focus cardiac ultrasound: the European Association of Cardiovascular Imaging viewpoint. Eur Heart J Cardiovasc Imaging 15:956–960

    Article  PubMed  Google Scholar 

  3. Neskovic AN, Skinner H, Price S, Via G, De Hert S, Stankovic I, Galderisi M, Donal E, Muraru D, Sloth E, Gargani L, Cardim N, Stefanidis A, Cameli M, Habib G, Cosyns B, Lancellotti P, Edvardsen T, Popescu BA, Reviewers: This document was reviewed by members of the 2016–2018 EACVI Scientific Documents Committee (2018) Focus cardiac ultrasound core curriculum and core syllabus of the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 19:475–481

    Article  PubMed  Google Scholar 

  4. Martocchia A, Bentivegna E, Sergi D, Luciani M, Barlattani M, Notarangelo MF, Piccoli C, Sesti G, Martelletti P (2023) The point-of-care ultrasound (POCUS) by the handheld ultrasound devices (HUDs) in the COVID-19 scenario: a review of the literature. SN Compr Clin Med 5:1. https://doi.org/10.1007/s42399-022-01316-9

    Article  CAS  PubMed  Google Scholar 

  5. Quinones MA, Waggoner AD, Reduto LA, Nelson JG, Young JB, Winters WL, Ribeiro LG, Miller RR (1981) A new, simplified and accurate method for determining ejection fraction with two-dimensional echocardiography. Circulation 64:744–753

    Article  CAS  PubMed  Google Scholar 

  6. Kosaraju A, Goyal A, Grigorova Y, Makaryus AN (2023) Left ventricular ejection fraction. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK459131/

  7. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W (2015) Voigt JU (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 28:1–39. https://doi.org/10.1016/j.echo.2014.10.003. (e14)

    Article  PubMed  Google Scholar 

  8. Starling MR, Walsh RA (1985) Accuracy of biplane axial oblique and oblique cineangiographic left ventricular cast volume determinations using a modification of Simpson’s rule algorithm. Am Heart J 110:1219–1225

    Article  CAS  PubMed  Google Scholar 

  9. Giavarina D (2015) Understanding Bland Altman analysis. Biochem Med (Zagreb) 25:141–151

    Article  PubMed  Google Scholar 

  10. Martocchia A, Ialungo S, Dulcetti A, Malena DM, Proietta M, Del Porto F, Landolfi F, Sesti G, Sergi D, Martelletti P (2022) The evaluation of the intracavitary effusions by a bedside ultrasound examination. Clin Hemorheol Microcirc 81:233–240

    Article  CAS  PubMed  Google Scholar 

  11. Filipiak-Strzecka D, Kasprzak JD, Wejner-Mik P, Szymczyk E, Wdowiak-Okrojek K, Lipiec P (2021) Artificial intelligence-powered measurement of left ventricular ejection fraction using a handheld ultrasound device. Ultrasound Med Biol 47:1120–1125

    Article  PubMed  Google Scholar 

  12. Maheshwarappa HM, Mishra S, Kulkarni AV, Gunaseelan V, Kanchi M (2021) Use of handheld ultrasound device with artificial intelligence for evaluation of cardiorespiratory system in COVID-19. Indian J Crit Care Med 25:524–527

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Nilsson G, Söderström L, Alverlind K, Samuelsson E, Mooe T (2019) Hand-held cardiac ultrasound examinations performed in primary care patients by nonexperts to identify reduced ejection fraction. BMC Med Educ 19:282. https://doi.org/10.1186/s12909-019-1713-9

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Wastl D, Löwe A, Dietrich CF (2022) Echoscopy in scanning cardiac diseases in critical care medicine. Med Klin Intensivmed Notfmed. https://doi.org/10.1007/s00063-022-00935-3. (Epub ahead of print. PMID: 35691992)

    Article  PubMed  Google Scholar 

  15. Cullen MW, Geske JB, Anavekar NS, Askew JW III, Lewis BR, Oh JK (2017) Handheld echocardiography during hospitalization for acute myocardial infarction. Clin Cardiol 40:993–999

    Article  PubMed  PubMed Central  Google Scholar 

  16. Dadon Z, Levi N, Alpert EA, Orlev A, Belman D, Glikson M, Butnaru A, Gottlieb S (2022) The quality, safety, feasibility, and interpretive accuracy of echocardiographic and lung ultrasound assessment of COVID-19 patients using a hand-held ultrasound. Echocardiography 39:886–894

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

The authors would like to thank the Emergency Medicine Unit, and, in particular, Rosalba Benvenuto, Massimiliano Rocchietti March, Laura Tafaro and Alberto Sentimentale, for their support in the study.

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Correspondence to Antonio Martocchia.

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Martocchia, A., Piccoli, C., Notarangelo, M.F. et al. The measurement of the left ventricle ejection fraction by a bedside FoCUS examination. Intern Emerg Med 18, 2253–2259 (2023). https://doi.org/10.1007/s11739-023-03414-5

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