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A bridge too far: are thrombolytics warranted as pre-treatment for endovascular therapy in acute ischemic stroke?

  • THE CUTTING EDGE: RESEARCH UPDATE
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References

  1. Powers WJ, Rabinstein AA, Ackerson T et al (2019) Guidelines for the early management of patients with acute ischemic stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 50:344–418. https://doi.org/10.1161/STR.0000000000000211

    Article  Google Scholar 

  2. Jang KM, Choi HH, Jang MJ, Cho YD (2021) Direct endovascular thrombectomy alone vs. bridging thrombolysis for patients with acute ischemic stroke: a meta-analysis. Clin Neuroradiol. https://doi.org/10.1007/s00062-021-01116-z

    Article  PubMed  Google Scholar 

  3. Shea BJ, Reeves BC, Wells G et al (2017) AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ 358:4008. https://doi.org/10.1136/bmj.j4008

    Article  Google Scholar 

  4. Cranston JS, Kaplan BD, Saver JL (2017) Minimal clinically important difference for safe and simple novel acute ischemic stroke therapies. Stroke 48(11):2946–2951. https://doi.org/10.1161/STROKEAHA.117.017496

    Article  PubMed  Google Scholar 

  5. Strong B, Oostema JA, Nikroo N, Hussain M, Reeves MJ (2021) Early termination of acute stroke randomized controlled trials published between 2013 and 2020: a systematic review. Circ Cardiovasc Qual Outcomes 14(12):007995. https://doi.org/10.1161/CIRCOUTCOMES.121.007995

    Article  Google Scholar 

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Funding

None of the authors have financial or non-financial interests directly or indirectly related to the submitted manuscript. No funding was received for this project.

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Authors and Affiliations

  1. Department of Emergency Medicine, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Manitoba, Canada

    Patrick E. Boreskie & Devon L. Johnstone

  2. Department of Emergency Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada

    Eddy Lang

Authors
  1. Patrick E. Boreskie
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  2. Devon L. Johnstone
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  3. Eddy Lang
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Correspondence to Patrick E. Boreskie.

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Boreskie, P.E., Johnstone, D.L. & Lang, E. A bridge too far: are thrombolytics warranted as pre-treatment for endovascular therapy in acute ischemic stroke?. Intern Emerg Med 17, 1517–1519 (2022). https://doi.org/10.1007/s11739-022-02990-2

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  • DOI: https://doi.org/10.1007/s11739-022-02990-2

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