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2D longitudinal LV speckle tracking strain pattern in breast cancer survivors: sports activity vs exercise as prescription model

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Abstract

Prevention strategies are important to optimize and to manage heart care in breast cancer survivors. Regular physical activity at moderate intensity is normally proposed to maintain myocardial performance; however, no data is available about the different impact of different levels of physical exercise. 2D speckle tracking echocardiography (2DSTE) is an accepted method for early detection of myocardial dysfunction. The study aims to monitor the cardiac performances in breast cancer survivors by 2DSTE analysis to manage sports activity vs physical activity. Two groups of previous breast cancer survivors (33 BCS) trained at moderate intensity and 55 athletes practicing dragon boat (DBA) sport were enrolled. They were matched with two healthy subjects groups: 23 competitive female athletes practicing different sports and 20 healthy women trained with exercise as prescription model. All women were studied by a complete echo examination including LV global longitudinal strain (GLS) assessment (XStrain-Esaote). EF and GS are only significantly higher in healthy subjects (−25.4 ± 2.1). Nevertheless, GLS values are within the normal range for all groups. Particularly, GS does not show any significant differences among subjects (−19.93 ± 4) practicing exercise as prescription when compared to the DBA competitive trained group. 2DSTE method is an appropriate method to supervise the intensity of exercise in breast cancer patients. Particularly, GLS can optimize and improve cancer therapy supporting and creating efficiencies within the health system confirming the role of the exercise prescription therapy in maintaining normal heart function.

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Acknowledgements

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Authors and Affiliations

  1. Sports Medicine Center, University of Florence, Florence, Italy

    Giorgio Galanti & Laura Stefani

  2. Architectural and Engineering Civil Department, University of Trieste, Trieste, Italy

    Gianni Pedrizzetti

  3. Medical Affairs, ESAOTE-S.p.A, Florence, Italy

    Stefano Pedri

Authors
  1. Giorgio Galanti
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  2. Gianni Pedrizzetti
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  3. Stefano Pedri
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  4. Laura Stefani
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Contributions

GG has deeply implemented the aim of the study contributing to the meaning in the exercise prescription application; GP has supported the statistical approach of the study, the significance of the strain analysis and the application of the method in this context; SP has strongly supported the technical aspects of the method used in terms of validity of the system; LS has conceived, written and revised the study. She has also coordinated the planning of protocol.

Corresponding author

Correspondence to Laura Stefani.

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The authors declare that they have no conflict of interest.

Statement of human and animal rights

The protocol was approved by the local ethical committee, in agreement with the Human and animal rights statement.

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All the subjects enrolled gave their consent to participate to the investigation.

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Galanti, G., Pedrizzetti, G., Pedri, S. et al. 2D longitudinal LV speckle tracking strain pattern in breast cancer survivors: sports activity vs exercise as prescription model. Intern Emerg Med 12, 1149–1157 (2017). https://doi.org/10.1007/s11739-017-1741-6

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  • DOI: https://doi.org/10.1007/s11739-017-1741-6

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