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Mitochondrial Replacement Therapy: An Islamic Perspective

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Abstract

Mitochondrial replacement technology (MRT) is an emerging and complex bioethical issue. This treatment aims to eliminate maternal inherited mitochondrial DNA (mtDNA) disorders. For Muslims, its introduction affects every aspect of human life, especially the five essential interests of human beings—namely, religion, life, lineage, intellect, and property. Thus, this technology must be assessed using a comprehensive and holistic approach addressing these human essential interests. Consequently, this article analyses and assesses tri-parent baby technology from the perspective of Maqasidic bioethics—that is, Islamic bioethics based on the framework of Maqasid al-Shariah. Using this analysis, this article suggests that tri-parent baby technology should not be permitted for Muslims due to the existence of third-party cell gametes which lead to lineage mixing and due to the uncertain safety of the therapy itself and because the major aim of the technology is to fulfil the affected couples interest to conceive their own genetically healthy child, not to treat and cure mtDNA disorders sufferers.

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Notes

  1. subhanahu wa ta'ala (The most glorified, the most high)

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Authors and Affiliations

  1. Programme of Applied Science with Islamic Studies, Academy of Islamic Studies, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Abdul Halim Ibrahim

  2. Department of Fiqh and Usul, Academy of Islamic Studies, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Noor Naemah Abdul Rahman

  3. Centre for Science and Environment Studies, Institute of Islamic Understanding Malaysia, 2 Langgak Tunku Off Jalan Tuanku Abdul Halim, 50480, Kuala Lumpur, Malaysia

    Shaikh Mohd Saifuddeen

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  1. Abdul Halim Ibrahim
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  2. Noor Naemah Abdul Rahman
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  3. Shaikh Mohd Saifuddeen
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Ibrahim, A.H., Rahman, N.N.A. & Saifuddeen, S.M. Mitochondrial Replacement Therapy: An Islamic Perspective. Bioethical Inquiry 20, 485–495 (2023). https://doi.org/10.1007/s11673-023-10279-y

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