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Le cellule staminali mesenchimali nel trattamento delle lesioni muscolo-tendinee

Mesenchymal stem cells in the treatment of muscle-tendon injuries

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LO SCALPELLO-OTODI Educational

Abstract

Tendon injuries are a cause of physical disability, especially in athletes. The challenge for orthopaedic surgeons is owed to the fact that injured tendons respond poorly to conventional treatments and stem-cell-based therapies may offer great potential to promote tendon regeneration tanks toh their proliferative, synthetic, and immunomodulatory activities. This work was aimed at providing an update on the current role and future directions of stem-cell-based therapies, discussing clinical cases. In spite of positive outcomes, additional clinical trials are needed to confirm the safety and efficacy of the treatment.

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Authors and Affiliations

  1. Orto-Traumatologia, P.O. Santa Maria delle Grazie, ASL Na2-Nord, Napoli, Italia

    A. Scotto di Luzio, D. Riccardi & A. P. D’Amato

  2. Anestesia-Rianimazione, P.O. Santa Maria delle Grazie, ASL Na2-Nord, Napoli, Italia

    F. Peluso

Authors
  1. A. Scotto di Luzio
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  2. S. Di Franco
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  3. F. Peluso
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  4. D. Riccardi
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  5. A. P. D’Amato
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Corresponding author

Correspondence to A. Scotto di Luzio.

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Conflitto di interesse

Gli autori A. Scotto di Luzio A, S. Di Franco, F. Peluso, D. Riccardi e A.P. D’Amato dichiarano di non aver alcun conflitto d’interesse.

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Tutte le procedure descritte nello studio e che hanno coinvolto essere umani sono state attuate in conformità alle norme etiche stabilite dalla dichiarazione di Helsinki del 1975 e successive modifiche. Il consenso informato è stato ottenuto da tutti i pazienti inclusi nello studio.

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L’articolo non contiene alcuno studio eseguito su esseri umani e su animali da parte degli autori.

Additional information

S. Di Franco is resident M.D. Trainee in Anesthesiology, Independent Researcher.

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Scotto di Luzio, A., Di Franco, S., Peluso, F. et al. Le cellule staminali mesenchimali nel trattamento delle lesioni muscolo-tendinee. LO SCALPELLO 33, 275–283 (2019). https://doi.org/10.1007/s11639-019-00332-0

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  • DOI: https://doi.org/10.1007/s11639-019-00332-0

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