ABSTRACT
BACKGROUND
Urine drug testing (UDT) can help identify misuse or diversion of opioid medications among patients with chronic pain. However, misinterpreting results can lead to false reassurance or erroneous conclusions about drug use.
OBJECTIVE
To examine the relationship between resident physicians’ knowledge about UDT interpretation and confidence in their ability to interpret UDT results.
DESIGN
Cross-sectional survey.
PARTICIPANTS
Internal medicine residents in a university health system in the Bronx, from 2010 to 2011.
MAIN MEASURES
We assessed knowledge using a 7-item scale (UDT knowledge score), and confidence in UDT interpretation using a single statement (“I feel confident in my ability to interpret the results of urine drug tests”). We conducted chi-square tests, t-tests, and logistic regression to determine the association between knowledge and confidence, and in exploratory analyses to examine whether resident characteristics (gender, training level, and UDT use) moderated the relationship between knowledge and confidence.
KEY RESULTS
Among 99 residents, the mean UDT knowledge score was 3.0 out of 7 (SD 1.2). Although 55 (56 %) of residents felt confident in their ability to interpret UDT results, 40 (73 %) of confident residents had a knowledge score of 3 or lower. Knowledge score was not associated with confidence among the full sample or when stratified by training level or UDT use. The association between knowledge and confidence differed significantly by gender (interaction term p < 0.01). Adjusting for training level and UDT use, knowledge was positively associated with confidence among females (AOR 1.79, 95 % CI: 1.06, 3.30), and negatively associated with confidence among males (AOR 0.47, 95 % CI: 0.23, 0.98).
CONCLUSIONS
Despite poor knowledge about UDT interpretation, most resident physicians felt confident in their ability to interpret UDT results. Gender differences warrant further exploration, but even confident physicians who use UDT should evaluate their proficiency in interpreting UDT results. Educational initiatives should emphasize the complexities of UDT interpretation.
Similar content being viewed by others
REFERENCES
Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Treatment Episode Data Set (TEDS) Highlights-- 2006 National Admissions to Substance Abuse Treatment Services. OAS Series #S-40, DHHS Publication No. (SMA) 08–4313, Rockville, MD, 2007; http://www.samhsa.gov/data/TEDS2k6highlights/TOC.htm. Accessed 10 July 2012.
Paulozzi LJ, Budnitz DS, Xi Y. Increasing deaths from opioid analgesics in the United States. Pharmacoepidemiol Drug Saf. 2006;15:618–27.
Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers-- United States, 1999–2008. In: MMWR Morb Mortal Wkly Rep. 4 Nov 2011 ed:1487–92.
Chou R, Fanciullo GJ, Fine PG, et al. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain. 2009;10:113–30.
Utah Department of Health. Utah Clinical Guidelines on Prescribing Opioids for Treatment of Pain. Salt Lake City, UT, 2009; http://www.dopl.utah.gov/licensing/forms/OpioidGuidlines.pdf Accessed 10 July 2012.
Trescot AM, Helm S, Hansen H, et al. Opioids in the management of chronic non-cancer pain: an update of American Society of the Interventional Pain Physicians' (ASIPP) Guidelines. Pain Physician. 2008;11:S5–62.
Washington State Agency Medical Directors' Group. Interagency Guideline on Opioid Dosing for Chronic Non-Cancer Pain. 2010; http://www.agencymeddirectors.wa.gov/Files/OpioidGdline.pdf Accessed 10 July 2012.
McLellan AT, Turner B. Prescription opioids, overdose deaths, and physician responsibility. JAMA. 2008;300:2672–3.
Atluri S, Sudarshan G. Evaluation of abnormal urine drug screens among patients with chronic non-malignant pain treated with opioids. Pain Physician. 2003;6:407–9.
Fishbain DA, Cutler RB, Rosomoff HL, Rosomoff RS. Validity of self-reported drug use in chronic pain patients. Clin J Pain. 1999;15:184–91.
Katz N, Fanciullo GJ. Role of urine toxicology testing in the management of chronic opioid therapy. Clin J Pain. 2002;18:S76–82.
Berndt S, Maier C, Schütz H-W. Polymedication and medication compliance in patients with chronic non-malignant pain. Pain. 1993;52:331–9.
Schuckman H, Hazelett S, Powell C, Steer S. A validation of self-reported substance use with biochemical testing among patients presenting to the emergency department seeking treatment for backache, headache, and toothache. Subst Use Misuse. 2008;43:589–95.
Katz NP, Sherburne S, Beach M, et al. Behavioral monitoring and urine toxicology testing in patients receiving long-term opioid therapy. Anesth Analg. 2003;97:1097–102.
Starrels JL, Becker WC, Alford DP, Kapoor A, Williams AR, Turner BJ. Systematic review: treatment agreements and urine drug testing to reduce opioid misuse in patients with chronic pain. Ann Intern Med. 2010;152:712–20.
Heit HA, Gourlay DL. Urine drug testing in pain medicine. J Pain Symptom Manag. 2004;27:260–7.
Gilbert JW, Wheeler GR, Mick GE, et al. Importance of urine drug testing in the treatment of chronic noncancer pain: implications of recent medicare policy changes in kentucky. Pain physician. 13:167–86.
Reisfield GM, Salazar E, Bertholf RL. Rational use and interpretation of urine drug testing in chronic opioid therapy. Ann Clin Lab Sci. 2007;37:301–14.
Moeller KE, Lee KC, Kissack JC. Urine drug screening: practical guide for clinicians. Mayo Clin Proc. 2008;83:66–76.
Tenore PL. Advanced urine toxicology testing. J Addict Dis. 2010;29:436–48.
Melanson SE, Kredlow MI, Jarolim P, Melanson SEF, Kredlow MI, Jarolim P. Analysis and interpretation of drug testing results from patients on chronic pain therapy: a clinical laboratory perspective. Clin Chem Lab Med. 2009;47:971–6.
Reisfield GM, Webb FJ, Bertholf RL, Sloan PA, Wilson GR. Family physicians' proficiency in urine drug test interpretation. J Opioid Manag. 2007;3.
Levy S, Harris SK, Sherritt L, Angulo M, Knight JR. Drug testing of adolescents in ambulatory medicine: physician practices and knowledge. Arch Pediatr Adolesc Med. 2006;160:146–50.
Duffy FD, Holmboe ES. Self-assessment in lifelong learning and improving performance in practice: physician know thyself. JAMA. 2006;296:1137–9.
Davis DA, Mazmanian PE, Fordis M, Van Harrison R, Thorpe KE, Perrier L. Accuracy of physician self-assessment compared with observed measures of competence: a systematic review. JAMA. 2006;296:1094–102.
Blanch DC, Hall JA, Roter DL, Frankel RM. Medical student gender and issues of confidence. Patient Educ Couns. 2008;72:374–81.
Lundeberg MA. Highly Confident, but Wrong: Gender Differences and Similarities in Confidence Judgments. Annual Meeting of the American Educational Research Association. San Francisco, CA, 1992; http://eric.ed.gov/PDFS/ED347899.pdf Accessed 10 July 2012.
Nomura K, Yano E, Fukui T. Gender differences in clinical confidence: a nationwide survey of resident physicians in Japan. Acad Med. 85:647–53.
Harris JM Jr, Fulginiti JV, Gordon PR, et al. KnowPain-50: a tool for assessing physician pain management education. Pain Med. 2008;9:542–54.
Yanni LM, Weaver MF, Johnson BA, Morgan LA, Harrington SE, Ketchum JM. Management of chronic nonmalignant pain: a needs assessment in an internal medicine resident continuity clinic. J Opioid Manag. 2008;4:201–11.
Reisfield GM. Urine drug test interpretation: what do physicians know? J Opioid Manag. 2007;3:80–6.
Berner ES, Graber ML. Overconfidence as a cause of diagnostic error in medicine. Am J Med. 2008;121:S2–23.
Christo PJ, Manchikanti L, Ruan X, et al. Urine drug testing in chronic pain. Pain Physician. 2011;14:123–43.
Cone EJ, Caplan YH, Cone EJ, Caplan YH. Urine toxicology testing in chronic pain management. Postgraduate Med. 2009;121:91–102.
Isaacson JH, Fleming M, Kraus M, Kahn R, Mundt M. A national survey of training in substance use disorders in residency programs. J Stud Alcohol. 2000;61:912–5.
Fleming MF, Manwell LB, Kraus M, Isaacson JH, Kahn R, Stauffacher EA. Who teaches residents about the prevention and treatment of substance use disorders? A national survey. J Fam Pract. 1999;48:725–9.
Miller NS, Sheppard LM, Colenda CC, Magen J. Why physicians are unprepared to treat patients who have alcohol- and drug-related disorders. Acad Med. 2001;76:410–8.
Lynch JR, Schmale GA, Schaad DC, Leopold SS. Important demographic variables impact the musculoskeletal knowledge and confidence of academic primary care physicians. J Bone Joint Surg Am. 2006;88:1589–95.
Haywood BL, Porter SL, Grana WA. Assessment of musculoskeletal knowledge in primary care residents. Am J Orthop (Belle Mead NJ). 2006;35:273–5.
Pergolizzi J, Pappagallo M, Stauffer J, et al. The role of urine drug testing for patients on opioid therapy. Pain Pract. 2010;10:497–507.
Bornstein BH, Emler AC. Rationality in medical decision making: a review of the literature on doctors' decision-making biases. J Eval Clin Pract. 2001;7:97–107.
Shults TF. The Medical Review Officer Handbook, Ninth Edition. Research Triangle Park, NC: Quadrangle Research, LLC; 2009.
Acknowledgments
This work was funded by the Health Research and Service Administration (D58 HP10330) and National Institute on Drug Abuse (K23 DA027719). The authors acknowledge the contributions of Bryan Wu, MS and Adenike Esho, MPH for participant recruitment, survey administration, and data management; Yuming Ning, PhD for statistical programming and analysis; Rachel Stark, MD, MPH for help conceptualizing and implementing the project; Moonseong Heo, PhD, Julia Arnsten, MD, MPH, and Barbara J. Turner, MD, MSc, MSEd for their mentorship, and the Montefiore Division of General Internal Medicine Substance Abuse Affinity Group for feedback during manuscript preparation. This work was presented as a poster at the 35th Annual Meeting of the Society for General Internal Medicine in Orlando, FL on May 11, 2012.
Conflicts of Interest
The authors declare that they do not have a conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Starrels, J.L., Fox, A.D., Kunins, H.V. et al. They Don’t Know What They Don’t Know: Internal Medicine Residents’ Knowledge and Confidence in Urine Drug Test Interpretation for Patients with Chronic Pain. J GEN INTERN MED 27, 1521–1527 (2012). https://doi.org/10.1007/s11606-012-2165-7
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11606-012-2165-7