Abstract
Purpose
This study aimed to assess radiological findings of adenomyomatosis advancing to chronic inflammation to differentiate between adenomyomatosis with and without chronic inflammation.
Materials and methods
We retrospectively identified 79 patients with pathologically proven adenomyomatosis without (n = 10) or with chronic inflammation (n = 69), who underwent computed tomography (CT) and magnetic resonance imaging (MRI) followed by surgery. MRI analysis included evaluation of GB wall-thickening type, presence and location of intramural cysts, and presence of stones. CT analysis included GB wall-thickening type only. Multivariate logistic regression analysis was used to identify the image-based findings of adenomyomatosis associated with chronic inflammation.
Results
On univariate analysis, MRI-based GB wall-thickening type and presence of stones, and CT-based GB wall-thickening type were significantly different between adenomyomatosis with and without chronic inflammation. On multivariate analysis, only the absence of stones was identified as a significant predictor of adenomyomatosis without chronic inflammation (odds ratio 5.58; 95% confidence interval 1.20–26.01; p = 0.029). There was no significant difference in other MRI- and CT-based findings between adenomyomatosis with and without chronic inflammation.
Conclusion
In patients with adenomyomatosis, the presence of stones was independently associated with chronic inflammation.
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Lee, H., Chung, WS., Kim, J.Y. et al. Chronic inflammation-related radiological findings of gallbladder adenomyomatosis. Jpn J Radiol 38, 463–471 (2020). https://doi.org/10.1007/s11604-020-00931-7
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DOI: https://doi.org/10.1007/s11604-020-00931-7