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A comparative study between arterial spin labeling and CT perfusion methods on hepatic portal venous flow

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Abstract

Purpose

The purpose of this study was to evaluate the feasibility and potential usefulness of unenhanced magnetic resonance (MR) hepatic portal perfusion using arterial spin labeling (ASL) among healthy volunteers and hepatocellular carcinoma patients.

Materials and methods

The five healthy volunteers underwent unenhanced MR perfusion with inversion time 2 (TI2) values at 500-ms intervals between 2,000 and 4,000 ms, and the 12 patients underwent unenhanced MR perfusion using ASL and computed tomography (CT) perfusion during superior mesenteric artery (SMA) portography. The regions of interest were placed in both the right and left lobes of the liver or both the right anterior and posterior segments of the liver and were placed over the tumor if a lesion was located within a particular perfusion study slice.

Results

In the healthy volunteer study, perfusion rate in hepatic parenchyma showed a peak at the TI2 value of 3,000 ms (254.3 ml/min/100 g ± 58.3). In patients, a fair correlation was observed between CT and MR perfusion (r = 0.795, P < 0.01).

Conclusion

Our results demonstrate a significant fair correlation between unenhanced MR hepatic portal perfusion imaging using ASL and CT perfusion during SMA portography.

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Acknowledgments

We thank Tsubasa Kaji, Siemens Japan K.K., for technical assistance.

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Authors and Affiliations

  1. Department of Radiology, Dokkyo Medical University Koshigaya Hospital, 2-1-50, Minami-Koshigaya, Koshigaya, Saitama, 343-8555, Japan

    Yoshiaki Katada, Toshiro Shukuya, Miho Kawashima & Miwako Nozaki

  2. Siemens Japan K.K., Takanawa Park Tower, 3-20-14, Higashi-Gotanda, Shinagawa-ku, Tokyo, 141-8644, Japan

    Hiroshi Imai

  3. Second Department of Surgery, Dokkyo Medical University Koshigaya Hospital, 2-1-50, Minami-Koshigaya, Koshigaya, Saitama, 343-8555, Japan

    Takeshi Natori

  4. Department of Gastroenterology, Dokkyo Medical University Koshigaya Hospital, 2-1-50, Minami-Koshigaya, Koshigaya, Saitama, 343-8555, Japan

    Masaya Tamano

Authors
  1. Yoshiaki Katada
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  2. Toshiro Shukuya
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  3. Miho Kawashima
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  4. Miwako Nozaki
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  5. Hiroshi Imai
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  6. Takeshi Natori
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  7. Masaya Tamano
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Corresponding author

Correspondence to Yoshiaki Katada.

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Katada, Y., Shukuya, T., Kawashima, M. et al. A comparative study between arterial spin labeling and CT perfusion methods on hepatic portal venous flow. Jpn J Radiol 30, 863–869 (2012). https://doi.org/10.1007/s11604-012-0127-y

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  • DOI: https://doi.org/10.1007/s11604-012-0127-y

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