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Zygomycotic invasion of the central nervous system

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Abstract

Zygomycosis is an opportunistic fungal infection that affects the central nervous system (CNS). In this report, we present three cases of zygomycosis with CNS involvement. In two patients zygomycosis developed after neurosurgery, and in the third patient zygomycosis developed after bone marrow transplantation for leukemia. All patients developed persistent fever and neurological deficits. They presented with progressive cerebral infarction accompanied by hemorrhage. Intraoperative findings and histopathological examinations revealed that zygomycotic hyphae caused mycotic aneurysm, vasculitis, and venous occlusion.

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Correspondence to Tomoaki Sasaki.

Additional information

These findings were presented at the annual meeting of the Japan Radiological Society, April 2009.

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Sasaki, T., Mineta, M., Kobayashi, K. et al. Zygomycotic invasion of the central nervous system. Jpn J Radiol 28, 376–380 (2010). https://doi.org/10.1007/s11604-010-0435-z

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  • DOI: https://doi.org/10.1007/s11604-010-0435-z

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