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Development of a porous reduced graphene oxide modified electrode for simultaneous determination of dopamine and uric acid

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Abstract

Porous reduced graphene oxide (pr-GO) exhibits good electrical conductivity, higher surface area and higher sensitivity. Herein, we have synthesized pr-GO by solution combustion method and characterized by XRD, FT-IR, SEM, Raman and absorption spectral studies used for the simultaneous determination of dopamine (DA) and uric acid (UA). The pr-GO-modified electrode showed good electrocatalytic activity and separated well the oxidation peaks of DA and UA. A simple and sensitive differential pulse voltammetric method was proposed for the simultaneous determination of DA and UA in the range of 0.5–470.8 µM and 0.1–450.1 µM, respectively, at pr-GO-modified electrode with LOD (s/n = 3) values of 0.031 µM and 0.060 µM for DA and UA, respectively.

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Acknowledgements

Thanks are due to SAIF, Karnatak University, Dharwad, for instrumental facilities. One of the authors, Mr. Naveenkumar P Agadi, thanks the Karnatak University for awarding the University Research Fellowship.

Funding

This study received financial support from the Council of Scientific and Industrial Research (CSIR), New Delhi, ref. No. 01 (3068)/21/EMR-II dated 23–8-2021.

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Authors and Affiliations

  1. Department of Chemistry, Karnatak University, Dharwad, 580 003, India

    Naveenkumar P. Agadi, Ranjita Tandel & J. Seetharamappa

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  1. Naveenkumar P. Agadi
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  2. Ranjita Tandel
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  3. J. Seetharamappa
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Contributions

Naveenkumar P. Agadi: conceptualization, data curation, software, formal analysis and writing—original draft preparation. Ranjita Tandel: visualization and editing. J. Seetharamappa: supervision, funding acquisition, methodology, investigation, project administration, resources and validation. All authors have read and agreed to the published version of the manuscript.

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Correspondence to J. Seetharamappa.

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Agadi, N.P., Tandel, R. & Seetharamappa, J. Development of a porous reduced graphene oxide modified electrode for simultaneous determination of dopamine and uric acid. Ionics 29, 4863–4873 (2023). https://doi.org/10.1007/s11581-023-05192-8

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