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Electrospun composite nanofibrous membrane as wound dressing with good adhesion

  • Research Article
  • Published:
Frontiers of Chemistry in China

Abstract

A photopolymerizationable mimic mussel protein structure monomer, dopamine methacrylamide (DMA), was synthesized. The photopolymerization of DMA was analysed by series real time near infrared spectroscopy (SRTIR). Dopamine methacrylamide/poly (ethylene oxide) (DMA/PEO) nanofibers were successfully prepared by electrospinning of aqueous DMA/PEO solution. Biocompatible nanofibrous membrane with good adhesion was produced by photocuring from the DMA/PEO nanofibers. The surface characterization and structure of the composite nanofibrous membrane were characterized by a scanning electron microscopy (SEM) and contact angle measurements. For identifying the potential crystalline of curing, a XRD method was used through comparing diffraction data. In the cell adhesion test we utilized the mouse fibroblast (L929) to exam the various use of the nanofibrous membrane as scaffolding materials for skin regeneration.

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Authors and Affiliations

  1. Key Laboratory of Carbon Fiber and Functional Polymers, Ministry of Education State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, China

    Rui Niu, Jing Qiao, Hang Yu, Jun Nie & Dongzhi Yang

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  1. Rui Niu
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  2. Jing Qiao
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  3. Hang Yu
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  4. Jun Nie
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  5. Dongzhi Yang
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Corresponding author

Correspondence to Dongzhi Yang.

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Niu, R., Qiao, J., Yu, H. et al. Electrospun composite nanofibrous membrane as wound dressing with good adhesion. Front. Chem. China 6, 221–226 (2011). https://doi.org/10.1007/s11458-011-0244-7

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  • DOI: https://doi.org/10.1007/s11458-011-0244-7

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