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In vitro and in vivo evaluation of porous NiTi alloy modified by sputtering a surface TiO2 film

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Abstract

A uniform and dense TiO2 film was grown on the surface of porous NiTi shape memory alloys (SMAs) successfully by RF magnetron sputtering. The morphology and composition of the surface film were analyzed by using scanning electron microscopy and X-ray photoelectron spectroscopy. The corrosion resistance measurement proved that the surface modified porous NiTi SMAs exhibit better corrosion resistance and over 25% reduction of Ni ion release in the blood of the rabbits in comparing with the samples without surface modification. Moreover, the biocompatibility, as demonstrated by cell adherence and implant surgery, revealed that the cell adherence and bone tissue inducing capability are respectively enhanced over 1.1–1.2 and 9–10 times by sputtering a uniform TiO2 film on the surfaces of porous NiTi SMAs.

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Authors and Affiliations

  1. School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China

    Bin Yuan, Hao Li, Yan Gao & Min Zhu

  2. Department of Physics & Materials Science, City University of Hong Kong, Kowloon, Hong Kong, China

    ChiYuen Chung

Authors
  1. Bin Yuan
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  2. Hao Li
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  3. Yan Gao
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  4. ChiYuen Chung
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  5. Min Zhu
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Correspondence to Min Zhu.

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Yuan, B., Li, H., Gao, Y. et al. In vitro and in vivo evaluation of porous NiTi alloy modified by sputtering a surface TiO2 film. Sci. China Technol. Sci. 55, 437–444 (2012). https://doi.org/10.1007/s11431-011-4683-7

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  • DOI: https://doi.org/10.1007/s11431-011-4683-7

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