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Chinese Society of Cardiology guidelines on the diagnosis and treatment of adult fulminant myocarditis

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Abstract

Fulminant myocarditis is an acute diffuse inflammatory disease of myocardium. It is characterized by acute onset, rapid progress and high risk of death. Its pathogenesis involves excessive immune activation of the innate immune system and formation of inflammatory storm. According to China’s practical experience, the adoption of the “life support-based comprehensive treatment regimen” (with mechanical circulation support and immunomodulation therapy as the core) can significantly improve the survival rate and long-term prognosis. Special emphasis is placed on very early identification,very early diagnosis,very early prediction and very early treatment.

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Acknowledgement

This work was supported in part by the National Natural Science Foundation of China (81790624, 81630010) and Top-Notch Talent Program of Hubei Province and Tongji Hospital (2021YBJRC005). We thank all the menbers of secretary group for their hard work: Zheng Wen, Luyun Wang, Houjuan Zuo, Kun Miao, Hongyang Shu, Jiahui Fan.

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Authors and Affiliations

  1. Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Jiangang Jiang, Hongyang Shu, Dao Wen Wang, Xiao Ran, Hong Wang, Guanglin Cui, Ning Zhou, Guoping Wang, Liming Xia, Yan Wang, Chunxia Zhao, Sheng Li, Hu Ding, Hesong Zeng, Li Lin & Xiaomei Guo

  2. Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China

    Rutai Hui

  3. Zhongnan Hospital of Wuhan University, Wuhan, 430062, China

    Chenze Li

  4. Fuwai Huazhong Cardiovascular Hospital, Zhengzhou, 450003, China

    Jing Zhang

  5. Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China

    Shaoping Nie

  6. Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, 510010, China

    Dingcheng Xiang

  7. Harbin Medical University Cancer Hospital, Harbin, 150081, China

    Qun Shao & Zhiren Zhang

  8. Union Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China

    Shengyong Xu

  9. Taida Hospital, Tianjin, 300457, China

    Yuming Li

  10. Peking University Third Hospital, Beijing, 100191, China

    Wei Gao

  11. Qilu Hospital of Shandong University, Jinan, 250012, China

    Yuguo Chen & Yuan Bian

  12. Kanghua Hospital, Dongguan, Guangzhou, 523080, China

    Yuhua Zhao

  13. Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310003, China

    Jianan Wang

  14. Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China

    Shaoliang Chen

  15. Renmin Hospital of Wuhan University, Wuhan, 430060, Wuhan, China

    Hong Jiang, Jing Chen & Xianjin Du

  16. West China Hospital, Sichuan University, Chengdu, 610044, China

    Mao Chen

  17. First Hospital of China Medical University, Shenyang, 110002, China

    Yinxian Sun

  18. General Hospital of Ningxia Medical University, Yinchuan, 750003, China

    Xueping Ma

  19. The Second Xiangya Hospital, Central South University, Changsha, 410012, China

    Shenghua Zhou

  20. The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230002, China

    Likun Ma

  21. The First Affiliated Hospital of Air Force Medical University, Xi’an, 710032, China

    Ling Tao

  22. Central Hospital of Wuhan City, Wuhan, 430014, China

    Juan Chen

  23. Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China

    Yiwu Zhou

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  1. Jiangang Jiang
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Consortia

Chinese Society of Cardiology, Chinese Medical Association, Writing Group

Corresponding author

Correspondence to Dao Wen Wang.

Ethics declarations

The formulation of this guideline was entrusted and assigned by the Chinese Society of Cardiology, undertaken by the Emergency and Critical Care Group of the Chinese Society of Cardiology, and written and discussed by senior experts and clinical front-line experts from multiple medical centers and disciplines across the country, including the Department of Cardiology, Department of Critical Care Medicine, Department of Pathology, Department of Rehabilitation, and Department of Imaging. The preparation of this guideline is supported by the Chinese Medical Association and the National Natural Science Foundation of China, and there is no commercial conflict of interest.

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Chinese Society of Cardiology, Chinese Medical Association, Writing Group., Jiang, J., Shu, H. et al. Chinese Society of Cardiology guidelines on the diagnosis and treatment of adult fulminant myocarditis. Sci. China Life Sci. (2024). https://doi.org/10.1007/s11427-023-2421-0

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