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Comorbidities are associated with self-reported sleep-disordered breathing and insomnia: a cross-sectional study from China

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Abstract

Purpose

We aimed to examine the associations of comorbidities with self-reported sleep-disordered breathing (SDB) and insomnia among Chinese adults.

Methods

The study used data from a community-based cross-sectional survey performed in China in 2018–2020. Multivariable logistic regression models were used to analyze the associations of 12 comorbidities with SDB and insomnia.

Results

A total of 4329 Han Chinese adults aged ≥ 18 years were enrolled. Of these, 1970 (45.5%) were male, with a median age of 48 years (interquartile range: 34–59). Compared with the participants without any conditions, adjusted ORs for SDB and insomnia for those with ≥ 4 comorbidities were 2.33 (95% CI: 1.58, 3.43, P-trend < 0.001) and 3.89 (95% CI: 2.69, 5.64, P-trend < 0.001), respectively. Seven comorbidities (hypertension, hyperlipidemia, coronary heart disease (CHD), bone and joint disease, neck or lumbar disease, chronic digestive diseases, and chronic urological disease) were positively associated with both SDB and insomnia. Cancer and chronic obstructive pulmonary disease (COPD) were also independently associated with insomnia. Of all comorbidities, cancer was most strongly associated with insomnia (OR = 3.16; 95% CI: 1.78, 5.63; P < 0.001), and CHD was most strongly associated with SDB (OR = 1.77; 95% CI: 1.19, 2.64; P < 0.001).

Conclusions

The findings showed that adults with an increasing number of comorbidities had higher odds for SDB and insomnia, which were independent of sociodemographic and lifestyle factors.

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Data availability

The original data supporting the conclusions of this article will be available by the authors, without reservation.

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Acknowledgements

The authors would like to thank the Suzhou Center for Disease Control and Prevention (CDC), and the local CDCs and communities in each district for their support of the survey.

Author information

Authors and Affiliations

  1. School of Public Health, Suzhou Medical College of Soochow University, 199 Ren’ai Rd., Suzhou, 215123, China

    Shengnan Li, Siyue Tan, Dong Liu, Ke Zhang, Yuyi Zhang & Hui Zuo

  2. Suzhou Center for Disease Control and Prevention, 72 San’xiang Rd., Suzhou, 215004, China

    Bo Wang

  3. Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, China

    Hui Zuo

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  1. Shengnan Li
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  2. Siyue Tan
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  3. Dong Liu
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  4. Ke Zhang
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  6. Bo Wang
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Contributions

Shengnan Li formulated the research question, analyzed the data, interpreted the results and drafted the manuscript. Shengnan Li, Yuyi Zhang, and Ke Zhang collected the data. Dong Liu, Siyue Tan proofread and revised the original manuscript. Bo Wang and Hui Zuo designed the study and revised the manuscript.

Corresponding authors

Correspondence to Bo Wang or Hui Zuo.

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The studies involving human participants were reviewed and approved by Ethics Committee of Suzhou Center for Disease Control and Prevention (SZJK2018-YY001) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Li, S., Tan, S., Liu, D. et al. Comorbidities are associated with self-reported sleep-disordered breathing and insomnia: a cross-sectional study from China. Sleep Breath 27, 2407–2413 (2023). https://doi.org/10.1007/s11325-023-02875-4

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  • DOI: https://doi.org/10.1007/s11325-023-02875-4

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